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Journal of Long-Term Effects of Medical Implants

年間 4 号発行

ISSN 印刷: 1050-6934

ISSN オンライン: 1940-4379

SJR: 0.184 SNIP: 0.485 CiteScore™:: 1.1 H-Index: 39

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Four-Year Follow-Up of Poly-L-Lactic Acid Cages for Lumbar Interbody Fusion in Goats

巻 15, 発行 2, 2005, pp. 125-138
DOI: 10.1615/JLongTermEffMedImplants.v15.i2.20
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要約

Background. New applications of bioabsorbable polymer implants demand for histologic evaluation because a host tissue response is elicited and late complications after polymer implantation have been reported. Furthermore, in load-bearing regions an accelerated polymer degradation and foreign body reaction may be observed. Methods. Lumbar interbody fusion procedures were performed using poly-L-lactic acid (PLLA) and titanium cages in 43 goats. At 3, 6, 12, 24, 36, and 48 months after surgery, sequential histologic analysis of instrumented motion segments, lymph nodes, and nervous structures was performed. Blood samples were retrieved for laboratory analysis. Results. No adverse local or distant histologic or systemic effects were observed during the absorption of the poly-L-lactic acid cages. Interbody fusion was maintained, and only a very mild inflammatory response was observed. In half the specimens complete absorption was observed, and in the remaining specimens an estimated 1−10% of the original PLLA was present at the 3-year follow-up. At the 4-year follow-up, five out of seven PLLA specimens showed no PLLA particles under polarized light microscopy. In the remaining two specimens an estimated 1% of the original PLLA could be observed. Conclusions. Poly-L-lactic acid cages are feasible for lumbar interbody fusion, and the biocompatibility under high load bearing conditions is excellent during the complete absorption of the PLLA interbody fusion cages.

によって引用された
  1. Wuisman Paul I.J.M., Krijnen Matthijs R., Helder Marco N., Smit Theo H., Letters, Spine, 30, 17, 2005. Crossref

  2. Smit Theo H., Engels Tom A. P., Wuisman Paul I. J. M., Govaert Leon E., Time-Dependent Mechanical Strength of 70/30 Poly(l,dl-lactide), Spine, 33, 1, 2008. Crossref

  3. Smit Theo H., Thomas Kevin A., Hoogendoorn Roel J. W., Strijkers Gustav J., Helder Marco N., Wuisman Paul I. J. M., Sterilization and Strength of 70/30 Polylactide Cages, Spine, 32, 7, 2007. Crossref

  4. Krijnen Matthijs R, Valstar E R, Smit Theo H, Wuisman Paul I J M, Does Bioresorbable Cage Material Influence Segment Stability in Spinal Interbody Fusion?, Clinical Orthopaedics and Related Research, 448, 2006. Crossref

  5. Mullender Margriet G., Krijnen Matthijs R., Helder Marco N., Smit Theo H., Everts Vincent, Wuisman Paul I.J.M., Lumbar body fusion with a bioresorbable cage in a goat model is delayed by the use of a carboxymethylcellulose-stabilized collagenous rhOP-1 device, Journal of Orthopaedic Research, 25, 1, 2007. Crossref

  6. Jiya Timothy, Smit Theo, Deddens James, Mullender Margriet, Posterior Lumbar Interbody Fusion Using Nonresorbable Poly-Ether-Ether-Ketone Versus Resorbable Poly-l-Lactide-Co-d,l-Lactide Fusion Devices, Spine, 34, 3, 2009. Crossref

  7. Hoogendoorn R. J. W., Lu Z. F., Kroeze R. J., Bank R. A., Wuisman P. I., Helder M. N., Adipose stem cells for intervertebral disc regeneration: current status and concepts for the future, Journal of Cellular and Molecular Medicine, 12, 6a, 2008. Crossref

  8. Lazennec Jean Y., Madi Abdallah, Rousseau Marc A., Roger Bernard, Saillant Gérard, Evaluation of the 96/4 PLDLLA polymer resorbable lumbar interbody cage in a long term animal model, European Spine Journal, 15, 10, 2006. Crossref

  9. Smit T. H., Engels T. A. P., Söntjens S. H. M., Govaert L. E., Time-dependent failure in load-bearing polymers: a potential hazard in structural applications of polylactides, Journal of Materials Science: Materials in Medicine, 21, 3, 2010. Crossref

  10. Krijnen Matthijs R., Mullender Margriet G., Smit Theo H., Everts Vincent, Wuisman Paul I. J. M., Radiographic, Histologic, and Chemical Evaluation of Bioresorbable 70/30 Poly-L-lactide-CO-D, L-lactide Interbody Fusion Cages in a Goat Model, Spine, 31, 14, 2006. Crossref

  11. Helder Marco N., Knippenberg Marlene, Klein-Nulend Jenneke, Wuisman Paul I.J.M., Stem Cells from Adipose Tissue Allow Challenging New Concepts for Regenerative Medicine, Tissue Engineering, 13, 8, 2007. Crossref

  12. van der Pol U., Mathieu L., Zeiter S., Bourban P.-E., Zambelli P.-Y., Pearce S.G., Bouré L.P., Pioletti D.P., Augmentation of bone defect healing using a new biocomposite scaffold: An in vivo study in sheep, Acta Biomaterialia, 6, 9, 2010. Crossref

  13. Smit T.H., Helder M.N., In vivo models of regenerative medicine in the spine, in Biomaterials for Spinal Surgery, 2012. Crossref

  14. Stübinger Stefan, Waser Jasmin, Hefti Thomas, Drechsler Anika, Sidler Michéle, Klein Karina, von Rechenberg Brigitte, Schlottig Falko, Evaluation of local cancellous bone amelioration by poly-l-dl-lactide copolymers to improve primary stability of dental implants: a biomechanical study in sheep, Clinical Oral Implants Research, 26, 5, 2015. Crossref

  15. Kroeze Robert J., Smit Theo H., Vergroesen Pieter P., Bank Ruud A., Stoop Reinout, van Rietbergen Bert, van Royen Barend J., Helder Marco N., Spinal fusion using adipose stem cells seeded on a radiolucent cage filler: a feasibility study of a single surgical procedure in goats, European Spine Journal, 24, 5, 2015. Crossref

  16. Kang Heesuk, Hollister Scott J., La Marca Frank, Park Paul, Lin Chia-Ying, Porous Biodegradable Lumbar Interbody Fusion Cage Design and Fabrication Using Integrated Global-Local Topology Optimization With Laser Sintering, Journal of Biomechanical Engineering, 135, 10, 2013. Crossref

  17. Pieske Oliver, Bauer Maximilian, Schröder Christian, Michaelis Ina, Massen Felix, Wallmichrath Jens, Suero Eduardo M., Greiner Axel, Development and biomechanical evaluation of a new biodegradable intramedullary implant for osteosynthesis of midshaft fractures of small hollow bones, Technology and Health Care, 28, 2, 2020. Crossref

  18. Han Xiao, Gao Yuan, Ding Yilei, Wang Weijie, Liu Li, Zhao Ansha, Yang Ping, In vitro performance of 3D printed PCL−β-TCP degradable spinal fusion cage, Journal of Biomaterials Applications, 35, 10, 2021. Crossref

  19. Fairag Rayan, Li Li, Ramirez-GarciaLuna Jose Luis, Taylor M. Scott, Gaerke Brian, Weber Michael H., Rosenzweig Derek H., Haglund Lisbet, A Composite Lactide-Mineral 3D-Printed Scaffold for Bone Repair and Regeneration, Frontiers in Cell and Developmental Biology, 9, 2021. Crossref

  20. Laubach Markus, Kobbe Philipp, Hutmacher Dietmar W., Biodegradable interbody cages for lumbar spine fusion: Current concepts and future directions, Biomaterials, 288, 2022. Crossref

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