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Journal of Environmental Pathology, Toxicology and Oncology

年間 4 号発行

ISSN 印刷: 0731-8898

ISSN オンライン: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

Indexed in

Modulatory Effect of Phenolic Fractions of Terminalia arjuna on the Mutagenicity in Ames Assay

巻 21, 発行 1, 2002, 12 pages
DOI: 10.1615/JEnvironPatholToxicolOncol.v21.i1.30
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要約

We determined the antimutagenicity of phenolic fractions of Terminalia arjuna (soluble and insoluble in chloroform) against two direct-acting mutagens, 4-nitro-o-phenylenediamine (NPD) and sodium azide, and against the S9-dependent mutagen 2-aminofluorene (2AF), in TA98 and TA100 tester strains of Salmonella typhimurium. We found that the phenolic fractions of T. arjuna inhibited revertants induced by the S9-dependent mutagen more remarkably than the direct-acting mutagens. Furthermore, the phenolic fractions showed maximum inhibition of 98% and 101.55%, respectively, in the pre-incubation mode of treatment against the mutations induced by 2AF. Overall, the fractions inhibited the revertants induced by S9-dependent mutagens more effectively than those induced by direct-acting mutagens. The percentage of inhibition was higher in the pre-incubation than with direct acting mutagens. The fraction insoluble in chloroform showed more inhibition than the soluble one, which corresponds to a higher polyphenol content in the insoluble fraction than in the soluble extract.

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  1. Pádua P.F.M.R., Dihl R.R., Lehmann M., de Abreu B.R.R., Richter M.F., de Andrade H.H.R., Genotoxic, antigenotoxic and phytochemical assessment of Terminalia actinophylla ethanolic extract, Food and Chemical Toxicology, 62, 2013. Crossref

  2. Paarakh Padmaa M, Terminalia arjuna (Roxb.) Wt. and Arn. : A Review, International Journal of Pharmacology, 6, 5, 2010. Crossref

  3. Sarabhai Sajal, Sharma Prince, Capalash Neena, Appanna Vasu D., Ellagic Acid Derivatives from Terminalia chebula Retz. Downregulate the Expression of Quorum Sensing Genes to Attenuate Pseudomonas aeruginosa PAO1 Virulence, PLoS ONE, 8, 1, 2013. Crossref

  4. Tilak Jai C., Devasagayam Thomas P.A., Adhikari Soumyakanti, Lele Ramachandra D., Kon Tatsuya, Handa Osamu, Naito Yuji, Yoshikawa Toshikazu, Cellular Membrane Protection Against Reactive Oxygen Species by Terminalia Arjuna and Its Active Component Baicalein, Journal of Clinical Biochemistry and Nutrition, 39, 2, 2006. Crossref

  5. Alkhuriji Afrah F., Alsaiari Seham G., Alomar Suliman Y., Alnafjan Alaa A., Alobaid Hussah, El-Khadragy Manal F., Effect of mesenchymal stem cells on cytochrome-c release and inflammation in colon cancer induced by 1,2-dimethylhydrazine in Wistar albino rats, Bioscience Reports, 41, 3, 2021. Crossref

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