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Journal of Environmental Pathology, Toxicology and Oncology

年間 4 号発行

ISSN 印刷: 0731-8898

ISSN オンライン: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

Indexed in

Copine 3 as a Novel Potential Drug Target for Non-Small-Cell Lung Carcinoma

巻 36, 発行 2, 2017, pp. 107-112
DOI: 10.1615/JEnvironPatholToxicolOncol.2017019540
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要約

Cancer originates from uncontrolled cell division in any part of the body. The universal burden of cancer continues to increase, and its treatment remains ever more challenging. Among several cancers, lung cancer is the second most common, causing 1.6 million deaths worldwide per year. Approximately 85% of lung cancers are non-small-cell lung carcinomas (NSCLCs), which are considerably more difficult to treat than other cancers. Although various imaging, biopsy, and histopathological analyses are widely used, there are no effective or reliable biomarkers for detecting early lung carcinoma, particularly NSCLC. For this reason, the identification of novel biomarkers to serve as therapeutic targets is essential to NSCLC treatment. Copines are a family of membrane-binding proteins that are highly conserved, soluble, ubiquitously expressed, calcium dependent, and found in variety of eukaryotic organisms. Recent research suggests that they may mediate various signaling pathways involved in both tumor progression and metastasis. In the copine gene family, copine 3 is a novel player in regulating NSCLC metastasis. This review highlights copine 3 as a prognostic marker as well as a potential therapeutic target for effective treatment of patients with NSCLC.

によって引用された
  1. El-Huneidi Waseem, Anjum Shabana, Mohammed Abdul Khader, Unnikannan Hema, Saeed Rania, Bajbouj Khuloud, Abu-Gharbieh Eman, Taneera Jalal, Copine 3 “CPNE3” is a novel regulator for insulin secretion and glucose uptake in pancreatic β-cells, Scientific Reports, 11, 1, 2021. Crossref

  2. Wang Qianchao, Jiang Meiqin, Isupov Michail N., Chen Yayu, Littlechild Jennifer A., Sun Lifang, Wu Xiuling, Wang Qin, Yang Wendi, Chen Lifei, Li Qi, Wu Yunkun, The crystal structure of Arabidopsis BON1 provides insights into the copine protein family, The Plant Journal, 103, 3, 2020. Crossref

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