RT Journal Article ID 565856cf415e6c30 A1 Hung, Mu-Chun A1 Tsai, Chia-Chun A1 Hsu, Tai-Hao A1 Liang, Zeng-Chin A1 Lin, Fang-Yi A1 Chang, Shih-Liang A1 Ho, Wai-Jane A1 Hsieh, Chang-Wei T1 Biological Activities of the Polysaccharides Produced from Different Sources of Xylaria nigripes (Ascomycetes), a Chinese Medicinal Fungus JF International Journal of Medicinal Mushrooms JO IJM YR 2015 FD 2015-02-26 VO 17 IS 2 SP 141 OP 150 K1 medicinal mushrooms and fungi K1 Xylaria nigripes K1 extracellular polysaccharide K1 intracellular polysaccharide K1 antioxidant AB Xylaria nigripes, a local rare medicinal fungus, has multi-antioxidant activities owing to its water extraction as shown by previous research. However, the main indicator causing the antioxidant effect was not clear, so this research focused on the antioxidant activities from different sources of X. nigripes such as fruiting body polysaccharides, mycelium intracellular polysaccharides, mycelium extracellular polysaccharides, and their deproteinization products. The mycelium intracellular polysaccharide (XnIPS-1) from X. nigripes showed the highest reducing power of antioxidant activity, since it revealed the lowest IC50 values in all the assayed methodologies. The IC50 values of chelating ferrous ion ability, ABTS radical scavenging activity, and DPPH free radical scavenging were 1412, 174.25, and 351.56 µg/mL, respectively. In addition to these results, this research also explored the mechanism between polysaccharides and antioxidants compared by FT-IR analysis. The spectrum shows that the X. nigripes polysaccharide structure changed after the proteins were removed. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,153df053409c56bf,565856cf415e6c30.html