RT Journal Article ID 03e8fd5c650f10a5 A1 Lai, Min-Nan A1 Ng, Lean-Teik T1 Antioxidant and Antiedema Properties of Solid-State Cultured Honey Mushroom, Armillaria mellea (Higher Basidiomycetes), Extracts and their Polysaccharide and Polyphenol Contents JF International Journal of Medicinal Mushrooms JO IJM YR 2013 FD 2013-03-08 VO 15 IS 1 SP 1 OP 8 K1 medicinal mushrooms K1 honey mushroom K1 Armillaria mellea K1 antiedema K1 antioxidant K1 polysaccharides K1 polyphenols AB Culinary-medicinal honey mushroom or Mi-Huan-Ku, Armillaria mellea (AM), is a popular ingredient in the traditional Chinese medicine for treating diseases of geriatric patients. This study aimed to examine the effect of cultured substrates on the mycelial growth of AM and evaluate its antioxidant and antiedema activities as well as its total polysaccharide and polyphenol contents. Results showed that AM grew best on the maize medium and worst on the potato medium. AM ethanol extract (AM-EtOH) showed stronger DPPH radical scavenging activity than AM aqueous extract (AM-H2O). However, they were weak in metal chelation and reducing power. AM-EtOH but not AM-H2O at 200 mg/kg showed antiedema activity in rats. The total β-glucan content of AM-H2O and AM-EtOH was 21.95% and 3.50%, respectively. AM-EtOH showed higher phenol but lower flavonoid content than AM-H2O. These results indicate that maize is a good source of substrate for mass production of AM mycelia, and its potency of DPPH radical scavenging and antiedema activities was contributed mainly by the phenolic compounds, not the level of polysaccharide content. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,30efbbbf6e2caad6,03e8fd5c650f10a5.html