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International Journal of Medicinal Mushrooms
IF: 1.423 5-Year IF: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Print: 1521-9437
ISSN Online: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.2019030123
pages 253-265

Engineering Aspects of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Biomass Submerged Cultivation in Bioreactors: A Review

Marin Berovic
Faculty of Chemistry and Chemical Engineering Department of Chemical and Biochemical Engineering University of Ljubljana Askerceva 5, 1001 Ljubljana, Slovenia
Bojana Boh Podgornik
Faculty of Natural Sciences and Engineering, University of Ljubljana, Vegova 4, 1000 Ljubljana, Slovenia

ABSTRACT

The Ganoderma lucidum wood-degrading basidiomycete, with its large complex of pharmacological effects, is the most outstanding and influential medicinal mushroom in Far East traditional medicine. In the past 2 decades, the fundamentals of submerged cultivation of G. lucidum mycelia in bioreactors has been established. Development of comprehensive submerged cultivations in stirred tank and air lift bioreactors are the most promising technologies. This article provides an engineering overview of the achievements in submerged technology of G. lucidum biomass production in bioreactors.


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