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International Journal of Medicinal Mushrooms
IF: 1.423 5-Year IF: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Print: 1521-9437
ISSN Online: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.2019030289
pages 225-235

The Potential Role of Medicinal Mushrooms in the Prevention and Treatment of Gynecological Cancers: A Review

Giuseppe Venturella
Department of Agricultural, Food and Forest Sciences, University of Palermo, Palermo, Italy
Paola Saporita
Department of Agricultural, Food and Forest Sciences, University of Palermo, Palermo, Italy
Maria Letizia Gargano
Department of Earth and Marine Sciences, University of Palermo, Bldg. 16, Viale delle Scienze, I-90128 Palermo, Italy

ABSTRACT

A review of scientific information about the potential role of medicinal mushrooms in the prevention and treatment of gynecological cancers, human immunodeficiency virus, and human papillomavirus infections is reported here. The results of in vivo and in vitro experiments on 16 different species of Basidiomycetes and three Ascomycetes, which possess chemopreventive potential and are effective in clinical application in combination with chemotherapy, are also discussed. Medicinal mushroom extracts confirm an evident efficacy on the reduction of tumor cell proliferation and side effects in patients with gynecological tumors who are undergoing chemotherapy treatments. This review, the first on the use of medicinal mushrooms in the prevention and treatment of gynecological cancers, aims to highlight the remarkable potential of mushrooms in integrated oncology.


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