Library Subscription: Guest
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections
International Journal of Medicinal Mushrooms
IF: 1.423 5-Year IF: 1.525 SJR: 0.431 SNIP: 0.716 CiteScore™: 2.6

ISSN Print: 1521-9437
ISSN Online: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v8.i2.20
pages 101-114

Emerging Antiviral Drugs from Medicinal Mushrooms

Frank F. Piraino
Department. of Visual Sciences, University of Wisconsin Medical School, Madison 517 Rupert Rd., Waunakee, WI. 53597, USA

ABSTRACT

Medicinal mushroom antivirals are a diverse group of chemical structures ranging from relatively low molecular weight compounds to high molecular weight carbohydrates and proteins. There is a paucity of information on the manner in which these antivirals interfere with viral replication. Mushroom-derived triterpenes and ubiquitin-associated peptides are examples of novel structures with potentially unique mechanisms of antiviral activity. Studies on these mechanisms will lead to the identification of targets for future drug development. Mushroom antivirals not previously reviewed are examined with these considerations in mind. Also reported here are original observations on the characterization and antiviral properties of a novel antiviral protein, RC 28, isolated from the mushroom Rozites caperatus. Elucidation of the antiviral mechanisms of mushroom antiviral drags are certain to advance the knowledge of viral replication and enhance the contribution of mushroom antivirals for the treatment of viral disease.


Articles with similar content:

The Development of the Antiviral Drug RC 28 from Rozites caperata (Pers.: Fr.) P. Karst. (Agaricomycetideae)
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Frank F. Piraino
Angiostatic Proteins and Peptides
Critical Reviews™ in Eukaryotic Gene Expression, Vol.11, 2001, issue 4
Kevin H. Mayo, Jessica C. A. Bouma-ter Steege, Arjan W. Griffioen
Anti-MRSA Activity of Fruiting Body Extracts of Spectacular Rustgill Mushroom, Gymnopilus junonius (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 3
Alvaro Vázquez, Graciela Borthagaray, María Pía Cerdeiras, Stephanie Barneche, Silvana Alborés
Antiviral Effect of Agaricomycetes Mushrooms (Review)
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 5
Tamara V. Teplyakova, Tatiana A. Kosogova
Oral Colon-Specific Drug Delivery of Protein and Peptide Drugs
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.24, 2007, issue 1
Ruchita V. Kumar, Sanjay Singh, Vivek Ranjan Sinha, J. R. Bhinge, Asmita Singh, Rachana Kumria