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International Journal of Physiology and Pathophysiology
SJR: 0.116

ISSN Print: 2155-014X
ISSN Online: 2155-0158

Archives: Volume 1, 2010 to Volume 9, 2018

International Journal of Physiology and Pathophysiology

DOI: 10.1615/IntJPhysPathophys.v8.i4.100
pages 375-388

Muscle Fatigue: Factors of Development and Ways of Prevention

Tetyana Yu. Matvienko
Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Danyloaniil A. Zavodovskyi
Taras Shevchenko National University, Kyiv, Ukraine
Dmytro N. Nozdrenko
Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Iryna V. Mishchenko
Lesya Ukrainka Eastern European National University, Lutsk, Ukraine
Olexander P. Motuziuk
Lesia Ukrainka Eastern European National University, Lutsk, Ukraine
Kateryna I. Bogutska
Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Yuriy I. Prylutskyy
Taras Shevchenko National University of Kyiv, Kyiv, Ukraine

ABSTRACT

In the review, the literature data regarding the analysis of physiological and biochemical mechanisms of muscle fatigue development and ways of its prevention are summarized. The effects of the most common endogenous and exogenous antioxidants on biochemical processes in muscle fatigue are analyzed. The review shows that biocompatible, non-toxic water-soluble C60 fullerenes, which possess powerful antioxidant properties, are capable of acting as promising means for correction of fatigue development in skeletal muscle caused by the destructive action of free radicals.


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