Library Subscription: Guest
Critical Reviews™ in Eukaryotic Gene Expression

Published 6 issues per year

ISSN Print: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Critical Review on Curcumin as a Therapeutic Agent: From Traditional Herbal Medicine to an Ideal Therapeutic Agent

Volume 28, Issue 1, 2018, pp. 17-24
DOI: 10.1615/CritRevEukaryotGeneExpr.2018020088
Get accessGet access

ABSTRACT

Traditionally, many natural medicinal plants have been used to treat a variety of diseases since ancient times and are considered a potential source of phytochemicals for the development of new drugs. One of these is curcumin, which is an easily accessible, inexpensive, and nontoxic bioactive compound. Curcumin is a very important, naturally occurring, and highly lipophilic and phenolic substance derived from the rhizomes of plant Curcuma longa, a member of the Zingiberaceae (ginger) family, which is mostly used as a curry spice, flavoring agent, insect repellent, coloring agent in food, traditional drug, and ingredient in cosmetics. Modern scientific research has demonstrated that it has wide range of pharmacological activities and medicinal properties against various types of diseases, disorders, and syndromes. Because it has been known for many years to have excellent therapeutic potential against various diseases, much research has been devoted to this natural product. This review briefly summarizes the scope, therapeutic potential and clinical applications of curcumin.

CITED BY
  1. Fifi Amanda, Axelrod Cara, Chakraborty Partha, Saps Miguel, Herbs and Spices in the Treatment of Functional Gastrointestinal Disorders: A Review of Clinical Trials, Nutrients, 10, 11, 2018. Crossref

  2. Izzo Angelo A., A PTR virtual issue on the experimental and clinical pharmacology of the nutraceutical curcumin, Phytotherapy Research, 32, 11, 2018. Crossref

  3. Akbar Muhammad Usman, Preparation, optimization and pharmacological evaluation of 99mTc- 4-hydroxy-3-(2-hydroxy-3-methoxybenzylideneamino) benzoic acid complex: as a novel potential radiopharmaceutical agent with hepatobiliary excretion, Molecular Biology Reports, 45, 6, 2018. Crossref

  4. Akbar Muhammad Usman, Zia Khalid Mahmood, Nazir Ahsan, Iqbal Jamshed, Ejaz Syeda Abida, Akash Muhammad Sajid Hamid, Pluronic-Based Mixed Polymeric Micelles Enhance the Therapeutic Potential of Curcumin, AAPS PharmSciTech, 19, 6, 2018. Crossref

  5. Akbar Muhammad Usman, Zia Khalid Mahmood, Akash Muhammad Sajid Hamid, Nazir Ahsan, Zuber Mohammad, Ibrahim Muhammad, In-vivo anti-diabetic and wound healing potential of chitosan/alginate/maltodextrin/pluronic-based mixed polymeric micelles: Curcumin therapeutic potential, International Journal of Biological Macromolecules, 120, 2018. Crossref

  6. Farooqui Tahira, Farooqui Akhlaq A., Potential Therapeutic Impacts of Curcumin for Improving Memory Impairment, in Curcumin for Neurological and Psychiatric Disorders, 2019. Crossref

  7. Zheng Bingjing, Zhang Xiaoyun, Peng Shengfeng, Julian McClements David, Impact of curcumin delivery system format on bioaccessibility: nanocrystals, nanoemulsion droplets, and natural oil bodies, Food & Function, 10, 7, 2019. Crossref

  8. Matos Jaqueline L, da Silva Karen R, Lima Paula Lucas A, Cunha Wilson R, Ramos Salvador B, Rodrigues Vanderlei, Cabral Fernanda J, Magalhães Lizandra G, Molluscicidal and cercaricidal activities of curcumin on Biomphalaria glabrata and Schistosoma mansoni cercariae , Pest Management Science, 76, 4, 2020. Crossref

  9. Yaghmur Anan, Nanoencapsulation of food ingredients by cubosomes and hexosomes, in Lipid-Based Nanostructures for Food Encapsulation Purposes, 2019. Crossref

  10. Akbar Muhammad Usman, Athar Muhammad Makshoof, Bhatti Ijaz Ahmad, Bhatti Haq Nawaz, Khosa Muhammad Kaleem, Mahmood Zia Khalid, Bokhari Tanveer Hussain, Ahmad Mirza Nadeem, Biomedical applications of bionanocomposites, in Bionanocomposites, 2020. Crossref

  11. Akbar Muhammad Usman, Zia Khalid Mahmood, Malik Muhammad Imran, Zahid Muhammad, Khera Rasheed Ahmad, Khaliq Zubair, Curcumin-based bionanocomposites, in Bionanocomposites, 2020. Crossref

  12. Basak Sanjay, Srinivas Vilasagaram, Mallepogu Aswani, Duttaroy Asim K., Curcumin stimulates angiogenesis through VEGF and expression of HLA‐G in first‐trimester human placental trophoblasts, Cell Biology International, 44, 5, 2020. Crossref

  13. Wicha Piyawadee, Tocharus Jiraporn, Janyou Adchara, Jittiwat Jinatta, Chaichompoo Waraluck, Suksamrarn Apichart, Tocharus Chainarong, Hexahydrocurcumin alleviated blood–brain barrier dysfunction in cerebral ischemia/reperfusion rats, Pharmacological Reports, 72, 3, 2020. Crossref

  14. Farooq Tahir, Hameed Arruje, Akash Muhammad Sajid Hamid, Rehman Kanwal, Polymer Coatings for Biomedical Applications, in Polymer Coatings, 2020. Crossref

  15. Su Ih-Jen, Chang Hong-Yi, Wang Hui-Chen, Tsai Kuen-Jer, A Curcumin Analog Exhibits Multiple Biologic Effects on the Pathogenesis of Alzheimer’s Disease and Improves Behavior, Inflammation, and β-Amyloid Accumulation in a Mouse Model, International Journal of Molecular Sciences, 21, 15, 2020. Crossref

  16. Thomas Jestin V., Smina Thozhuthum Parambil, Khanna Aman, Kunnumakkara Ajaikumar B., Maliakel Balu, Mohanan Ratheesh, Krishnakumar Illathu Madhavamenon, Influence of a low‐dose supplementation of curcumagalactomannoside complex ( CurQfen ) in knee osteoarthritis: A randomized, open‐labeled, active‐controlled clinical trial , Phytotherapy Research, 35, 3, 2021. Crossref

  17. Babaei Fatemeh, Nassiri‐Asl Marjan, Hosseinzadeh Hossein, Curcumin (a constituent of turmeric): New treatment option against COVID‐19, Food Science & Nutrition, 8, 10, 2020. Crossref

  18. Karthika Chenmala, Hari Balaji, Mano Vignesh, Radhakrishnan Arun, Janani S.K., Akter Rokeya, Kaushik Deepak, Rahman Md. Habibur, Curcumin as a great contributor for the treatment and mitigation of colorectal cancer, Experimental Gerontology, 152, 2021. Crossref

  19. Al-Jameel Suhailah Saud, The activity of curcumin combined with ZnCl₂ on streptozotocin-induced diabetic rats. An anti-diabetic, anti-hyperlipidemic study ‎, Journal Of Advanced Pharmacy Education And Research, 11, 1, 2021. Crossref

  20. Gano Marcin, Klebeko Joanna, Pełech Robert, Efficient esterification of curcumin in bis(trifluoromethylsulfonyl)imide-based ionic liquids, Journal of Molecular Liquids, 337, 2021. Crossref

  21. Duttaroy Asim K., Clinical use of curcumin, in Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease, 2021. Crossref

  22. AKKAYA Kemal, YILDIRIM Metin, DEĞİRMENCİ Ulaş, DOĞRUER ÜNAL Nil, Sıçanlarda Akrilonitril ile Oluşturulmuş Oksidatif Strese Karşı Timokinon ve Kurkuminin Olası Koruyucu Etkileri, Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi, 2021. Crossref

  23. Zia Khalid Mahmood, Akram Nadia, Tabasum Shazia, Noreen Aqdas, Akbar Muhammad Usman, Processing of bio-based polymers, in Processing Technology for Bio-Based Polymers, 2021. Crossref

  24. Daisy E.R. Anishiya Chella, Rajendran Naresh Kumar, Houreld Nicolette Nadene, Marraiki Najat, Elgorban Abdallah M., Rajan Mariappan, Curcumin and Gymnema sylvestre extract loaded graphene oxide-polyhydroxybutyrate‑sodium alginate composite for diabetic wound regeneration, Reactive and Functional Polymers, 154, 2020. Crossref

  25. Rehman Kanwal, Ali Mehwish Bagh, Akash Muhammad Sajid Hamid, Genistein enhances the secretion of glucagon-like peptide-1 (GLP-1) via downregulation of inflammatory responses, Biomedicine & Pharmacotherapy, 112, 2019. Crossref

  26. Amuti Aibibai, Wang Xue, Zan Mingyang, Lv Shaojun, Wang Zhanzhong, Formulation and characterization of curcumin-loaded microemulsions: Evaluation of antioxidant stability and in vitro release, Journal of Molecular Liquids, 336, 2021. Crossref

  27. Alesci Alessio, Aragona Marialuisa, Cicero Nicola, Lauriano Eugenia Rita, Can nutraceuticals assist treatment and improve covid-19 symptoms?, Natural Product Research, 36, 10, 2022. Crossref

  28. Akbar Muhammad U., Bokhari Tanveer H., Ahmad Muhammad R., Zia Khalid M., Roohi Samina, Ayub Nimra, Sohaib Muhammad, Radiosynthesis, radiochemical, and biological characterization of 177 Lu‐labeled diethylenetriamine penta‐acetic acid , Journal of Cellular Biochemistry, 120, 9, 2019. Crossref

  29. Hussain Yaseen, Islam Lubna, Khan Haroon, Filosa Rosanna, Aschner Michael, Javed Saba, Curcumin–cisplatin chemotherapy: A novel strategy in promoting chemotherapy efficacy and reducing side effects, Phytotherapy Research, 35, 12, 2021. Crossref

  30. Mahmood Saima, Bhattarai Prapanna, Khan Nauman Rahim, Subhan Zakia, Razaque Ghulam, Albarqi Hassan A., Alqahtani Abdulsalam A., Alasiri Ali, Zhu Lin, An Investigation for Skin Tissue Regeneration Enhancement/Augmentation by Curcumin-Loaded Self-Emulsifying Drug Delivery System (SEDDS), Polymers, 14, 14, 2022. Crossref

  31. Kiyama Ryoiti, Nutritional implications of ginger: chemistry, biological activities and signaling pathways, The Journal of Nutritional Biochemistry, 86, 2020. Crossref

  32. Shabbir Anam, Rehman Kanwal, Akbar Moazzama, Akash Muhammad Sajid Hamid, Neuroprotective Potential of Curcuminoids in Modulating Alzheimer’s Disease via Multiple Signaling Pathways, Current Medicinal Chemistry, 29, 34, 2022. Crossref

Forthcoming Articles

PRMT6 promotes the immune evasion of gastric cancer via upregulating ANXA1 Liang Xu, Fenger Zhang, Binqi Yu, Shengnan Jia, Sunfu Fan PURPL promotes M2 macrophage polarization in lung cancer via regulating RBM4/xCT signaling Jipeng Guo, Chongwen Gong, Hao Wang SIAH1 promotes the pyroptosis of cardiomyocytes in diabetic cardiomyopathy via regulating IκB-α/NF-κB signaling Jinbin Wu, Yaoming Yan SLC7A2-mediated lysine catabolism inhibits immunosuppression in triple negative breast cancer Yuanyuan Sun, Yaqing Li, Chengying Jiang, Chenying Liu, Yuanming Song SIAH2-mediated degradation of ACSL4 inhibits the anti-tumor activity of CD8+ T cells in hepatocellular carcinoma Fangzheng Shu, Yuhua Shi, Xiangxiang Shan, Wenzhang Zha, Rengen Fan, Wanjiang Xue RBM15-mediated N6-methyl adenosine (m6A) modification of EZH2 drives the epithelial-mesenchymal transition of cervical cancer Ruixue Wang, Wenhua Tan Evidence-Based Storytelling and A Strategic Roadmap to Promote Cancer Prevention Via Adolescent HPV Vaccination in Northern New England Matthew Dugan, Gary Stein, Jan Carney, Sheila Clifford-Bova KDM4A-AS1 promotes cell proliferation, migration and invasion via the miR-4306/STX6 axis in hepatocellular carcinoma Wei Cao, Yuhan Ren, Ying Liu, Guoshu Cao, Zhen Chen, Fan Wang HDAC1-mediated downregulation of NEU1 exacerbates the aggressiveness of cervical cancer Nanzi Xie, Sisi Mei, Changlan Dai, Wei Chen Effect of miR-26b-5p on progression of acute myeloid leukemia by regulating USP48-mediated Wnt/β-catenin pathway Yu Xie, Lin Tan, Kun Wu, Deyun Li, Chengping Li
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections Prices and Subscription Policies Begell House Contact Us Language English 中文 Русский Português German French Spain