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Critical Reviews™ in Eukaryotic Gene Expression

Published 6 issues per year

ISSN Print: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Long Non-Coding RNA Urothelial Carcinoma Associated 1 (UCA1): Insight into Its Role in Human Diseases

Volume 25, Issue 3, 2015, pp. 191-197
DOI: 10.1615/CritRevEukaryotGeneExpr.2015013770
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ABSTRACT

Long non-coding RNA (lncRNA) is a type of DNA transcript that is longer than 200 nucleotides (nt). They do not encode proteins, but they control gene expression on various levels. Long non-coding RNA metastasis-associated urothelial carcinoma associated 1 (UCA1) was confirmed to play an important role in the occurrence and development of many tumor and non-tumor diseases. UCA1 mainly interacts with proteins in the nucleus, regulating gene expression in transcription and post-transcription. UCA1 is highly expressed in tumor tissue, and therefore can be related to clinical parameters. It may regulate tumor cell proliferation, invasion, apoptosis, and migration, so UCA1 can be applied in clinical prognosis and targeted therapy. This review mainly elaborates the roles of UCA1 in tumor diseases of the respiratory, digestive, reproductive, and urinary systems; and in non-tumor diseases.

CITED BY
  1. Gao Ming, Li Changying, Xu Ming, Liu Yun, Liu Sijin, LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress, Toxicology Letters, 284, 2018. Crossref

  2. Gong Jianhua, Zhang Han, He Li, Wang Lixin, Wang Jipeng, Increased Expression of Long Non-Coding RNA BCAR4 Is Predictive of Poor Prognosis in Patients with Non-Small Cell Lung Cancer, The Tohoku Journal of Experimental Medicine, 241, 1, 2017. Crossref

  3. Zhu Fang-Fang, Zheng Fei-Yun, Wang Hai-Ou, Zheng Jing-Jie, Zhang Qian, Downregulation of lncRNA TUBA4B is Associated with Poor Prognosis for Epithelial Ovarian Cancer, Pathology & Oncology Research, 24, 2, 2018. Crossref

  4. Hua Qian, Mi Baoming, Huang Gang, The emerging co-regulatory role of long noncoding RNAs in epithelial-mesenchymal transition and the Warburg effect in aggressive tumors, Critical Reviews in Oncology/Hematology, 126, 2018. Crossref

  5. Li Ling, Zhuang Yingliang, Zhao Xingsen, Li Xuekun, Long Non-coding RNA in Neuronal Development and Neurological Disorders, Frontiers in Genetics, 9, 2019. Crossref

  6. Shao Hongfang, Jin Feng, Hu Jiangshan, Zhu Zhangying, Tian Fuju, Tao Minfang, Teng Yincheng, Urothelial carcinoma associated 1 promotes trophoblast invasion by regulating MMP9, Cell & Bioscience, 9, 1, 2019. Crossref

  7. Li Chengyun, Liang Geyu, Yang Sheng, Sui Jing, Yao Wenzhuo, Shen Xian, Zhang Yanqiu, Peng Hui, Hong Weiwei, Xu Siyi, Wu Wenjuan, Ye Yancheng, Zhang Zhiyi, Zhang Wenhua, Yin Lihong, Pu Yuepu, Dysregulated lncRNA-UCA1 contributes to the progression of gastric cancer through regulation of the PI3K-Akt-mTOR signaling pathway, Oncotarget, 8, 55, 2017. Crossref

  8. Wang Xiaoxiong, Peng Fei, Cheng Liang, Yang Guang, Zhang Daming, Liu Jiaqi, Chen Xin, Zhao Shiguang, Prognostic and clinicopathological role of long non-coding RNA UCA1 in various carcinomas, Oncotarget, 8, 17, 2017. Crossref

  9. Han Chaofei , Tang Fengjie , Chen Jia , Xu Dan , Li Xiong , Xu Yangcheng , Wang Shaohua , Zhou Jianda , Knockdown of lncRNA‑UCA1 inhibits the proliferation and migration of melanoma cells through modulating the miR‑28‑5p/HOXB3 axis, Experimental and Therapeutic Medicine, 2019. Crossref

  10. Shan Liping, Liu Wei, Zhan Yunhong, LncRNA HAND2-AS1 exerts anti-oncogenic effects on bladder cancer via restoration of RARB as a sponge of microRNA-146, Cancer Cell International, 21, 1, 2021. Crossref

  11. Zhou Xu, Cui Yu, Chen Jinbo, Li Chao, Chen Fengmin, Chen Xiang, Ou Zhenyu, Cheng Xu, Ren Wenbiao, Li Huihuang, Zu Xiongbing, Liu Nenghui, UCA1 promotes cell viability, proliferation and migration potential through UCA1/miR-204/CCND2 pathway in primary cystitis glandularis cells, Biomedicine & Pharmacotherapy, 114, 2019. Crossref

  12. Zhang Li, Tan Wei, Song Xinmiao, Wang Shanmei, Tang Liang, Chen Yu, Yu Hanqing, Jiang Ping, Liu Jinming, Methylprednisolone Attenuates Lipopolysaccharide-Induced Sepsis by Modulating the Small Nucleolar RNA Host Gene 5/Copine 1 Pathway, DNA and Cell Biology, 40, 11, 2021. Crossref

  13. Zhang Xiaobo, Gao Feng, Zhou Lei, Wang Huaitao, Shi Gang, Tan Xiaodong, UCA1 Regulates the Growth and Metastasis of Pancreatic Cancer by Sponging miR-135a, Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, 25, 9, 2017. Crossref

  14. Liu Congmin, Jin Jing, Shi Jin, Wang Liqun, Gao Zhaoyu, Guo Tiantian, He Yutong, Long noncoding RNA UCA1 as a novel biomarker of lymph node metastasis and prognosis in human cancer: a meta-analysis, Bioscience Reports, 39, 4, 2019. Crossref

  15. Jiang Siyu, Liu Yi, Xu Bilian, Zhang Yan, Yang Min, Noncoding RNAs: New regulatory code in chondrocyte apoptosis and autophagy, WIREs RNA, 11, 4, 2020. Crossref

  16. Li Dagang, Li Huizong, Yang Yuping, Kang Le, Long Noncoding RNA Urothelial Carcinoma-Associated 1 Promotes the Proliferation and Metastasis of Human Lung Tumor Cells by Regulating MicroRNA-144, Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, 26, 4, 2018. Crossref

  17. Yu Gangfeng, Xiong Dongmei, Liu Zhengshu, Li Yongguo, Chen Ke, Tang Hua, Retracted : Long noncoding RNA LINC00052 inhibits colorectal cancer metastasis by sponging microRNA‐574‐5p to modulate CALCOCO1 expression , Journal of Cellular Biochemistry, 120, 10, 2019. Crossref

  18. Cao Chen, Zhang Junhui, Yang Chuanhua, Xiang Lili, Liu Wenneng, Silencing of long noncoding RNA UCA1 inhibits colon cancer invasion, migration and epithelial‐mesenchymal transition and tumour formation by upregulating miR‐185‐5p in vitro and in vivo, Cell Biochemistry and Function, 38, 2, 2020. Crossref

  19. Hu Xiaorong, Ma Ruisong, Fu Wenwen, Zhang Changjiang, Du Xianjin, LncRNA UCA1 sponges miR‐206 to exacerbate oxidative stress and apoptosis induced by ox‐LDL in human macrophages, Journal of Cellular Physiology, 234, 8, 2019. Crossref

  20. Yu Yanlan, Gao Fengbin, He Qian, Li Gonghui, Ding Guoqing, lncRNA UCA1 Functions as a ceRNA to Promote Prostate Cancer Progression via Sponging miR143, Molecular Therapy - Nucleic Acids, 19, 2020. Crossref

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