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Critical Reviews™ in Eukaryotic Gene Expression

Published 6 issues per year

ISSN Print: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Epithelial Mesenchymal Transition and Vascular Mimicry in Breast Cancer Stem Cells

Volume 25, Issue 3, 2015, pp. 269-280
DOI: 10.1615/CritRevEukaryotGeneExpr.2015014042
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ABSTRACT

Vasculogenic mimicry (VM), a newly defined pattern of tumor microvascularization differs from angiogenesis and vasculogenesis in its noninvolvement of endothelial cells, by which highly aggressive tumor cells can form vessel-like structures themselves, because of their high plasticity. The presence of VM has been shown to be strongly associated with a poor prognosis in several types of cancer, but biological features of tumor cells that form VM remains unknown. Human breast cancer, characterized by a group of highly heterogeneous lesions, is the most common cancer in women and one of the leading causes of cancer-related deaths worldwide. The epithelialmesenchymal transition (EMT) state in breast cancer has been associated with cancer stem cell (CSC) properties, self-renewal capabilities, resistance to conventional therapies, and a tendency for posttreatment recurrence. With increasing knowledge about cancer stem cell phenotypes and functions, they are implicated in VM formation. Studies also indicate that EMT is relevant to the acquisition and maintenance of stem cell−like characteristics and is involved in VM. This review discusses the correlation between CSCs, EMT, and VM formation with a focus on breast cancer. Also, the signalling molecules and pathways involved in VM and some recently defined direct VM targeting strategies in breast cancer are reviewed here.

CITED BY
  1. Liu Qiqi, Qiao Lili, Liang Ning, Xie Jian, Zhang Jingxin, Deng Guodong, Luo Hui, Zhang Jiandong, The relationship between vasculogenic mimicry and epithelial-mesenchymal transitions, Journal of Cellular and Molecular Medicine, 20, 9, 2016. Crossref

  2. Yu Helen H., Featherston Therese, Tan Swee T., Chibnall Alice M., Brasch Helen D., Davis Paul F., Itinteang Tinte, Characterization of Cancer Stem Cells in Moderately Differentiated Buccal Mucosal Squamous Cell Carcinoma, Frontiers in Surgery, 3, 2016. Crossref

  3. Featherston Therese, Yu Helen H., Dunne Jonathan C., Chibnall Alice M., Brasch Helen D., Davis Paul F., Tan Swee T., Itinteang Tinte, Cancer Stem Cells in Moderately Differentiated Buccal Mucosal Squamous Cell Carcinoma Express Components of the Renin–Angiotensin System, Frontiers in Surgery, 3, 2016. Crossref

  4. Hong Ming, Tan Hor, Li Sha, Cheung Fan, Wang Ning, Nagamatsu Tadashi, Feng Yibin, Cancer Stem Cells: The Potential Targets of Chinese Medicines and Their Active Compounds, International Journal of Molecular Sciences, 17, 6, 2016. Crossref

  5. Nilendu Pritish, Kumar Ajay, Kumar Azad, Pal Jayanta K., Sharma Nilesh Kumar, Breast cancer stem cells as last soldiers eluding therapeutic burn: A hard nut to crack, International Journal of Cancer, 142, 1, 2018. Crossref

  6. Cavaco Ana, Rezaei Maryam, Niland Stephan, Eble Johannes A., Collateral Damage Intended—Cancer-Associated Fibroblasts and Vasculature Are Potential Targets in Cancer Therapy, International Journal of Molecular Sciences, 18, 11, 2017. Crossref

  7. Han Cong, Sun Baocun, Zhao Xiulan, Zhang Yanhui, Gu Qiang, Liu Fang, Zhao Nan, Wu Lili, Phosphorylation of STAT3 Promotes Vasculogenic Mimicry by Inducing Epithelial-to-Mesenchymal Transition in Colorectal Cancer, Technology in Cancer Research & Treatment, 16, 6, 2017. Crossref

  8. Yang Liuqi, Shang Zhengling, Long Shiqi, Wang Nianxue, Shan Ge, Zhang Ruya, Roles of genetic and microenvironmental factors in cancer epithelial-to-mesenchymal transition and therapeutic implication, Experimental Cell Research, 370, 2, 2018. Crossref

  9. Xu Mei, Wang Siying, Wang Yongchao, Wu Huaxun, Frank Jacqueline A., Zhang Zhuo, Luo Jia, Role of p38γ MAPK in regulation of EMT and cancer stem cells, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1864, 11, 2018. Crossref

  10. Tang Bo, Tian Yu, Liao Yong, Li Zeming, Yu Shuiping, Su Huizhao, Zhong Fudi, Yuan Guandou, Wang Yan, Yu Hongping, Tomlinson Stephen, Qiu Xiaoqiang, He Songqing, CBX8 exhibits oncogenic properties and serves as a prognostic factor in hepatocellular carcinoma, Cell Death & Disease, 10, 2, 2019. Crossref

  11. Guo Xing, Xu Shugang, Gao Xiao, Wang Jian, Xue Hao, Chen Zihang, Zhang Jinsen, Guo Xiaofan, Qian Mingyu, Qiu Wei, Li Gang, Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells, Oncotarget, 8, 46, 2017. Crossref

  12. Leng Xiaoling, Huang Guofu, Zhang Lianhua, Ding Jianbing, Ma Fucheng, Lu Wan Liang, Changes in Tumor Stem Cell Markers and Epithelial-Mesenchymal Transition Markers in Nonluminal Breast Cancer after Neoadjuvant Chemotherapy and Their Correlation with Contrast-Enhanced Ultrasound, BioMed Research International, 2020, 2020. Crossref

  13. Morales-Guadarrama Gabriela, García-Becerra Rocío, Méndez-Pérez Edgar Armando, García-Quiroz Janice, Avila Euclides, Díaz Lorenza, Vasculogenic Mimicry in Breast Cancer: Clinical Relevance and Drivers, Cells, 10, 7, 2021. Crossref

  14. He Xuejun, You Jijun, Ding Haibing, Zhang Zhisheng, Cui Lin, Shen Xiaomei, Bian Xiaoxia, Liu Yanqing, Chen Jue, Vasculogenic mimicry, a negative indicator for progression free survival of lung adenocarcinoma irrespective of first line treatment and epithelial growth factor receptor mutation status, BMC Cancer, 21, 1, 2021. Crossref

  15. Leng Xiaoling, Japaer Rexida, Zhang Haijian, Yeerlan Mila, Ma Fucheng, Ding Jianbing, Relationship of shear wave elastography anisotropy with tumor stem cells and epithelial-mesenchymal transition in breast cancer, BMC Medical Imaging, 21, 1, 2021. Crossref

  16. Herrera-Vargas Ana K., García-Rodríguez Eduardo, Olea-Flores Monserrat, Mendoza-Catalán Miguel A., Flores-Alfaro Eugenia, Navarro-Tito Napoleón, Pro-angiogenic activity and vasculogenic mimicry in the tumor microenvironment by leptin in cancer, Cytokine & Growth Factor Reviews, 62, 2021. Crossref

  17. Wang Hua, Huang Bin, Li Bai Mou, Cao Kai Yuan, Mo Chen Qiang, Jiang Shuang Jian, Pan Jin Cheng, Wang Zong Ren, Lin Huan Yi, Wang Dao Hu, Qiu Shao Peng, ZEB 1‐mediated vasculogenic mimicry formation associates with epithelial–mesenchymal transition and cancer stem cell phenotypes in prostate cancer , Journal of Cellular and Molecular Medicine, 22, 8, 2018. Crossref

  18. Morales-Guadarrama Gabriela, Méndez-Pérez Edgar A., García-Quiroz Janice, Avila Euclides, García-Becerra Rocío, Zentella-Dehesa Alejandro, Larrea Fernando, Díaz Lorenza, Endothelium-Dependent Induction of Vasculogenic Mimicry in Human Triple-Negative Breast Cancer Cells Is Inhibited by Calcitriol and Curcumin, International Journal of Molecular Sciences, 23, 14, 2022. Crossref

  19. Pouliquen Daniel L., Boissard Alice, Henry Cécile, Coqueret Olivier, Guette Catherine, Curcuminoids as Modulators of EMT in Invasive Cancers: A Review of Molecular Targets With the Contribution of Malignant Mesothelioma Studies, Frontiers in Pharmacology, 13, 2022. Crossref

  20. Bhattacharya Susinjan, Metabolic Reprogramming and Cancer: 2022, Qeios, 2022. Crossref

  21. Bhattacharya Susinjan, Metabolic Reprogramming and Cancer: 2022, Qeios, 2022. Crossref

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