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Critical Reviews™ in Eukaryotic Gene Expression

Published 6 issues per year

ISSN Print: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Critical Aspects of Tissue-Engineered Therapy for Bone Regeneration

Volume 11, Issue 1-3, 2001, 26 pages
DOI: 10.1615/CritRevEukarGeneExpr.v11.i1-3.90
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ABSTRACT

Recent advances in bone tissue engineering are established on the understanding of an engineered scaffold, the molecular milieu within the osteogenic site, and the cell(s) predisposed to an osteogenic lineage. Advances in the incorporation of a generative vehicle into a skeletal defect require temporal and spatial distribution of the scaffold, growth factor, and cell compatible with enhanced bone healing. Monitoring events culminating in osteogenesis has focused on phenotypic and intracellular indicators. Phenotypic and intracellular indicators include the presence of receptors and intracellular signals that enable cell proliferation and differentiation. Progress in the areas of scaffold design, growth factor utilization, bone cell lineage, and intracellular signaling are reviewed.

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  1. Gersbach Charles A., Guldberg Robert E., García Andrés J., In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts, Journal of Cellular Biochemistry, 100, 5, 2007. Crossref

  2. Gersbach Charles A., Byers Benjamin A., Pavlath Grace K., Guldberg Robert E., García Andrés J., Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro, Biotechnology and Bioengineering, 88, 3, 2004. Crossref

  3. Kim Soo-Woo, Ogawa Takahiro, Tabata Yasuhiko, Nishimura Ichiro, Efficacy and cytotoxicity of cationic-agent-mediated nonviral gene transfer into osteoblasts, Journal of Biomedical Materials Research, 71A, 2, 2004. Crossref

  4. Santoni Brandon G., Simon Turner A., Wheeler Donna L., Nicholas Richard W., Anchordoquy Tom J., Ehrhart Nicole, Gene Therapy to Enhance Allograft Incorporation After Host Tissue Irradiation, Clinical Orthopaedics and Related Research, 466, 8, 2008. Crossref

  5. Campana V., Milano G., Pagano E., Barba M., Cicione C., Salonna G., Lattanzi W., Logroscino G., Bone substitutes in orthopaedic surgery: from basic science to clinical practice, Journal of Materials Science: Materials in Medicine, 25, 10, 2014. Crossref

  6. Phillips Jennifer E., Guldberg Robert E., García Andrés J., Dermal Fibroblasts Genetically Modified to Express Runx2/Cbfa1 as a Mineralizing Cell Source for Bone Tissue Engineering, Tissue Engineering, 13, 8, 2007. Crossref

  7. Porter Joshua R., Ruckh Timothy T., Popat Ketul C., Bone tissue engineering: A review in bone biomimetics and drug delivery strategies, Biotechnology Progress, 2009. Crossref

  8. Harley Brendan A., Lynn Andrew K., Wissner-Gross Zachary, Bonfield William, Yannas Ioannis V., Gibson Lorna J., Design of a multiphase osteochondral scaffold. II. Fabrication of a mineralized collagen-glycosaminoglycan scaffold, Journal of Biomedical Materials Research Part A, 9999A, 2009. Crossref

  9. Chang Hsiao-Hua, Chang Mei-Chi, Wu I-Hua, Huang Guay-Fen, Huang Wei-Ling, Wang Yin-Lin, Lee Sheng-Yang, Yeh Chien-Yang, Guo Ming-Kuang, Chan Chiu-Po, Hsien Hsiang-Chi, Jeng Jiiang-Huei, Role of ALK5/Smad2/3 and MEK1/ERK Signaling in Transforming Growth Factor Beta 1–modulated Growth, Collagen Turnover, and Differentiation of Stem Cells from Apical Papilla of Human Tooth, Journal of Endodontics, 41, 8, 2015. Crossref

  10. Blum Jeremy S, Barry Michael A, Mikos Antonios G, Bone regeneration through transplantation of genetically modified cells, Clinics in Plastic Surgery, 30, 4, 2003. Crossref

  11. Leonor I. B., Azevedo Helena S., Alves Catarina M., Reis Rui L., Biomimetic Coatings: Biodegradable Polymer Application, in Encyclopedia of Biomedical Polymers and Polymeric Biomaterials, 2015. Crossref

  12. Unger Ronald E., Peters Kirsten, Huang Quan, Funk Andreas, Paul Dieter, Kirkpatrick C.J., Vascularization and gene regulation of human endothelial cells growing on porous polyethersulfone (PES) hollow fiber membranes, Biomaterials, 26, 17, 2005. Crossref

  13. Unger R.E., Peters K., Wolf M., Motta A., Migliaresi C., Kirkpatrick C.J., Endothelialization of a non-woven silk fibroin net for use in tissue engineering: growth and gene regulation of human endothelial cells, Biomaterials, 25, 21, 2004. Crossref

  14. Avula Mahender N., Grainger David W., Addressing Medical Device Challenges with Drug-Device Combinations, in Drug-Device Combinations For Chronic Diseases, 2015. Crossref

  15. Gruber Reinhard, Koch Hannjörg, Doll Bruce A., Tegtmeier Florian, Einhorn Thomas A., Hollinger Jeffrey O., Fracture healing in the elderly patient, Experimental Gerontology, 41, 11, 2006. Crossref

  16. Sato Yasuko, Kikuchi Masahiro, Ohata Noboru, Tamura Masato, Kuboki Yoshinori, Enhanced Cementum Formation in Experimentally Induced Cementum Defects of the Root Surface with the Application of Recombinant Basic Fibroblast Growth Factor in Collagen Gel In Vivo, Journal of Periodontology, 75, 2, 2004. Crossref

  17. Dunn Courtney A., Jin Qiming, Taba Mario, Franceschi Renny T., Bruce Rutherford R., Giannobile William V., BMP gene delivery for alveolar bone engineering at dental implant defects, Molecular Therapy, 11, 2, 2005. Crossref

  18. Yanagi Tsukasa, Kajiya Hiroshi, Kawaguchi Minoru, Kido Hirofumi, Fukushima Tadao, Photothermal stress triggered by near infrared-irradiated carbon nanotubes promotes bone deposition in rat calvarial defects, Journal of Biomaterials Applications, 29, 8, 2015. Crossref

  19. Lee Dong-Hyun, Kim Ji Wan, Bone Substitutes and the Advancement for Enhancing Bone Healing, Journal of the Korean Fracture Society, 30, 2, 2017. Crossref

  20. Szczepańczyk Piotr, Pielichowska Kinga, Chłopek Jan, Polyurethane composite foams with β-tricalcium phosphate for biomedical applications, Journal of Reinforced Plastics and Composites, 34, 22, 2015. Crossref

  21. Byers Benjamin A., Guldberg Robert E., García Andrés J., Synergy between Genetic and Tissue Engineering: Runx2 Overexpression and in Vitro Construct Development Enhance in Vivo Mineralization, Tissue Engineering, 10, 11-12, 2004. Crossref

  22. Minuth W.W., Strehl R., Schumacher K., Tissue Factory: Conceptual Design of a Modular System for the in Vitro Generation of Functional Tissues, Tissue Engineering, 10, 1-2, 2004. Crossref

  23. Partridge Kris A., Oreffo Richard O.C., Gene Delivery in Bone Tissue Engineering: Progress and Prospects Using Viral and Nonviral Strategies, Tissue Engineering, 10, 1-2, 2004. Crossref

  24. Clark Paul A., Moioli Eduardo K., Sumner D. Rick, Mao Jeremy J., Porous implants as drug delivery vehicles to augment host tissue integration, The FASEB Journal, 22, 6, 2008. Crossref

  25. Minuth W.W., Strehl R., Schumacher K., Microreactor Optimisation for Functional Tissue Engineering, in Bioreactors for Tissue Engineering, 2005. Crossref

  26. Karin Norman J., Farach-Carson Mary C., In Vitro Regulation of Osteoblast Activity, in Bone Formation, 2004. Crossref

  27. Gersbach Charles A., Phillips Jennifer E., García Andrés J., Genetic Engineering for Skeletal Regenerative Medicine, Annual Review of Biomedical Engineering, 9, 1, 2007. Crossref

  28. Lynn A. K., Bonfield W., A Novel Method for the Simultaneous, Titrant-Free Control of pH and Calcium Phosphate Mass Yield, Accounts of Chemical Research, 38, 3, 2005. Crossref

  29. Katsumata Yuri, Kajiya Hiroshi, Okabe Koji, Fukushima Tadao, Ikebe Tetsuro, A salmon DNA scaffold promotes osteogenesis through activation of sodium-dependent phosphate cotransporters, Biochemical and Biophysical Research Communications, 468, 4, 2015. Crossref

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