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Critical Reviews™ in Biomedical Engineering
SJR: 0.207 SNIP: 0.376 CiteScore™: 0.79

ISSN Print: 0278-940X
ISSN Online: 1943-619X

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.v28.i12.300
pages 179-185

Identification and Targeting Policies for Computer-Controlled Infusion Pumps

Andrea Gentilini
Automatic Control Laboratory, Swiss Federal Institute of Technology (ETH), CH-8092 Zurich, Switzerland
Christian W. Frei
Automatic Control Laboratory, Swiss Federal Institute of Technology (ETH), CH-8092 Zurich, Switzerland
Adolf H. Glattfelder
Automatic Control Laboratory, Swiss Federal Institute of Technology (ETH), CH-8092 Zurich, Switzerland
Manfred Morari
ETH Zurich, Institut fur Automatik, Physikstrasse 3, CH-8092, Switzerland
Thomas W. Schnider
Institut fur Anaesthesiologie und Intensivbehandlung, Inselspital, CH-3010 Bern, Switzerland

ABSTRACT

In this article a series of useful techniques is presented to improve the adaptation capabilities of computer-controlled infusion pumps: an identification algorithm for the time constant of the effect compartment, a smoothing technique for estimation based on noisy data, and an infusion policy to target any effect site concentration with no overshoot.


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