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Critical Reviews™ in Therapeutic Drug Carrier Systems

Published 6 issues per year

ISSN Print: 0743-4863

ISSN Online: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

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Polymeric Mixed Micelles: Improving the Anticancer Efficacy of Single-Copolymer Micelles

Volume 36, Issue 1, 2019, pp. 1-58
DOI: 10.1615/CritRevTherDrugCarrierSyst.2018020481
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ABSTRACT

Mixed micelles self-assembled from two or more dissimilar block copolymers provide a direct and convenient approach to improved drug delivery. The present review is focused on mixed micelles (prepared from block copolymers only) for various drug delivery applications along with their merits over single-copolymer micelles. Presented are the physicochemical properties of mixed and single-copolymer micelles, various stimuli-responsive mixed micelles for the treatment of cancer, interesting combinations of multifunctional mixed micelles along with their in vitro and in vivo performance, and the potential of mixed micelles as a gene delivery system. Finally, the performance of mixed micelles in preclinical and clinical testing is explained. In addition, the interaction of mixed micelles with cancer cells and the biosafety of mixed micelles are summarized. The in vitro and in vivo performance presented here clearly reveals that the mixed-micelle approach has a wider scope than that of the single-copolymer micelle approach and directs researchers to focus on this approach to delivery of drugs/gene/biologics for various applications.

CITED BY
  1. Jiang Shanshan, Mou Yanhua, He Huiyang, Yang Dandan, Qin Li, Zhang Fang, Zhang Peng, Preparation and evaluation of self-assembly Soluplus®-sodium cholate-phospholipid ternary mixed micelles of docetaxel, Drug Development and Industrial Pharmacy, 45, 11, 2019. Crossref

  2. Manjappa Arehalli S., Kumbhar Popat S., Kasabe Rohini, Diwate Sonali K., Disouza John I., Ameliorated in vitro anticancer efficacy of methotrexate d-α-Tocopheryl polyethylene glycol 1000 succinate ester against breast cancer cells, Future Journal of Pharmaceutical Sciences, 5, 1, 2019. Crossref

  3. König Nico, Willner Lutz, Lund Reidar, Structure and thermodynamics of mixed polymeric micelles with crystalline cores: tuning properties via co-assembly, Soft Matter, 15, 39, 2019. Crossref

  4. Kurmi Balak Das, Patel Preeti, Paliwal Rishi, Paliwal Shivani Rai, Molecular approaches for targeted drug delivery towards cancer: A concise review with respect to nanotechnology, Journal of Drug Delivery Science and Technology, 57, 2020. Crossref

  5. Bandgar Sandip A., Jadhav Namdeo R., Manjappa Arehalli S., A remarkable in vitro cytotoxic, cell cycle arresting and proapoptotic characteristics of low-dose mixed micellar simvastatin combined with alendronate sodium, Drug Delivery and Translational Research, 10, 4, 2020. Crossref

  6. Gudise Venkataiah, Chowdhury Bimalendu, Manjappa Arehalli S., Antidiabetic and antihyperlipidemic effects of Argyreia pierreana and Matelea denticulata: Higher activity of the micellar nanoformulation over the crude extract, Journal of Traditional and Complementary Medicine, 11, 3, 2021. Crossref

  7. Kumbhar Popat S., Sakate Asmita M., Patil Onkar B., Manjappa Arehalli S., Disouza John I., Podophyllotoxin-polyacrylic acid conjugate micelles: improved anticancer efficacy against multidrug-resistant breast cancer, Journal of the Egyptian National Cancer Institute, 32, 1, 2020. Crossref

  8. Kong Haiting, Li Yiqi, Wang Duo, Liu Hong, Pan Hongchun, Physicochemical parameters and thermodynamic behavior of aprepitant/HS15 micellar system at different temperatures: Effect of electrolytes concentration, Journal of Molecular Liquids, 328, 2021. Crossref

  9. Gontier Alice, Renou Frédéric, Colombani Olivier, Burel Fabrice, Morandi Gaëlle, Hybridization of Poly(oxazoline) and Poly(ethylene oxide)-Based Amphiphilic Copolymers into Thermosensitive Mixed Micelles of Tunable Cloud Point, Langmuir, 37, 39, 2021. Crossref

  10. Mena-Giraldo Pedro, Orozco Jahir, Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery, Polymers, 13, 22, 2021. Crossref

  11. Patil Kiran S., Hajare Ashok A., Manjappa Arehalli S., More Harinath N., Disouza John I., Design, development, in silico and in vitro characterization of Docetaxel-loaded TPGS/ Pluronic F 108 mixed micelles for improved cancer treatment, Journal of Drug Delivery Science and Technology, 65, 2021. Crossref

  12. Wang Duo, Wu Mei, Zhang Wei, Pan Hongchun, Liu Hong, Effects of different sterilization cooling procedures on thermodynamic stability of Coenzyme Q10-HS15 micelles and optimization strategy: Based on micellar CMC and interface properties, Journal of Molecular Liquids, 349, 2022. Crossref

  13. Kancharla Samhitha, Bedrov Dmitry, Tsianou Marina, Alexandridis Paschalis, Structure and composition of mixed micelles formed by nonionic block copolymers and ionic surfactants in water determined by small-angle neutron scattering with contrast variation, Journal of Colloid and Interface Science, 609, 2022. Crossref

  14. Nguyen Thi Lien, Ishihara Kazuhiko, Yusa Shin-ichi, Separated Micelles Formation of pH-Responsive Random and Block Copolymers Containing Phosphorylcholine Groups, Polymers, 14, 3, 2022. Crossref

  15. Chowdhury Suman, Rakshit Atanu, Acharjee Animesh, Kumar Dileep, Saha Bidyut, Anionic micelles and their ideal binary mixture: Worth media for sustainable oxidation of hydrophobic alcohol, Journal of Molecular Liquids, 346, 2022. Crossref

  16. Pérez Sebastián E., Haidar Ziyad S., Polymeric micelles: précis for past, present and future, in Polymeric Micelles for Drug Delivery, 2022. Crossref

  17. Patil Smita S., Chougale Rutuja D., Manjappa Arehalli S., Disouza John I., Hajare Ashok A., Patil Kiran S., Statistically developed docetaxel-laden mixed micelles for improved therapy of breast cancer, OpenNano, 8, 2022. Crossref

  18. Patil Kiran S., Hajare Ashok A., Manjappa Arehalli S., More Harinath N., Disouza John I., Design, Development, In Silico, and In Vitro Characterization of Camptothecin-Loaded Mixed Micelles: In Vitro Testing of Verapamil and Ranolazine for Repurposing as Coadjuvant Therapy in Cancer, Journal of Pharmaceutical Innovation, 2022. Crossref

  19. Ke Zhongcheng, Shi Jianjun, Cheng Ziyang, Cheng Xiaoling, Wang Huan, Wang Meng, Wu Jingjing, Sun Yinyu, Li Changjiang, Design and characterization of gambogic acid-loaded mixed micelles system for enhanced oral bioavailability, Pharmaceutical Development and Technology, 27, 6, 2022. Crossref

  20. Krawczyk-Santos Anna Paula, Marreto Ricardo Neves, Concheiro Angel, Alvarez-Lorenzo Carmen, Taveira Stephânia Fleury, Poly(pseudo)rotaxanes formed by mixed micelles and α-cyclodextrin enhance terbinafine nail permeation to deeper layers, International Journal of Pharmaceutics: X, 4, 2022. Crossref

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