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Critical Reviews™ in Therapeutic Drug Carrier Systems

Published 6 issues per year

ISSN Print: 0743-4863

ISSN Online: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

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Lipid-Based Cochleates: A Promising Formulation Platform for Oral and Parenteral Delivery of Therapeutic Agents

Volume 24, Issue 1, 2007, pp. 41-62
DOI: 10.1615/CritRevTherDrugCarrierSyst.v24.i1.20
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ABSTRACT

Cochleates are lipid-based supramolecular assemblies that display great potential as delivery systems for systemic delivery of drugs, including peptides, proteins, vaccines, oligonucleotides, and genes. This is mainly attributed to their high stability and biocompatibility and their ability to deliver both hydrophilic and lipophilic drugs. Cochleates have a unique multilayered spiral structure, which is composed of a negatively charged phospholipid and a divalent cation, and can encapsulate diverse drug molecules of various shapes and sizes while minimizing toxicity associated with polymeric materials present in micro- and nanoparticle systems. This review describes current technological advances in the preparation methods, physicochemical characterization, and potential applications of cochleates as a drug delivery system for systemic delivery of various types of therapeutic agents.

CITED BY
  1. Li Jing, Wang Xuling, Zhang Ting, Wang Chunling, Huang Zhenjun, Luo Xiang, Deng Yihui, A review on phospholipids and their main applications in drug delivery systems, Asian Journal of Pharmaceutical Sciences, 10, 2, 2015. Crossref

  2. Fricker Gert, Kromp Torsten, Wendel Armin, Blume Alfred, Zirkel Jürgen, Rebmann Herbert, Setzer Constanze, Quinkert Ralf-Olaf, Martin Frank, Müller-Goymann Christel, Phospholipids and Lipid-Based Formulations in Oral Drug Delivery, Pharmaceutical Research, 27, 8, 2010. Crossref

  3. Epand Raquel F., Mor Amram, Epand Richard M., Lipid complexes with cationic peptides and OAKs; their role in antimicrobial action and in the delivery of antimicrobial agents, Cellular and Molecular Life Sciences, 68, 13, 2011. Crossref

  4. Czerkinsky C, Holmgren J, Topical immunization strategies, Mucosal Immunology, 3, 6, 2010. Crossref

  5. Srivastava Atul, Gowda Devegowda Vishakante, Madhunapantula SubbaRao V., Shinde Chetan G., Iyer Meenakshi, Mucosal vaccines: a paradigm shift in the development of mucosal adjuvants and delivery vehicles, APMIS, 123, 4, 2015. Crossref

  6. Nagarsekar Kalpa, Ashtikar Mukul, Steiniger Frank, Thamm Jana, Schacher Felix, Fahr Alfred, Understanding cochleate formation: insights into structural development, Soft Matter, 12, 16, 2016. Crossref

  7. Nagarsekar Kalpa, Ashtikar Mukul, Steiniger Frank, Thamm Jana, Schacher Felix H., Fahr Alfred, Micro-spherical cochleate composites: method development for monodispersed cochleate system, Journal of Liposome Research, 27, 1, 2017. Crossref

  8. Fokina Alesya A., Chelobanov Boris P., Fujii Masayuki, Stetsenko Dmitry A., Delivery of therapeutic RNA-cleaving oligodeoxyribonucleotides (deoxyribozymes): from cell culture studies to clinical trials, Expert Opinion on Drug Delivery, 14, 9, 2017. Crossref

  9. Liu Min, Zhong Xiaoming, Yang Zhiwen, Chitosan functionalized nanocochleates for enhanced oral absorption of cyclosporine A, Scientific Reports, 7, 1, 2017. Crossref

  10. Batista-Duharte Alexander, Pereira Sandro Antonio, Freitas Dayvison Francis Saraiva, Fuentes Deivys Portuondo, Gutierrez-Galhardo Maria Clara, Carlos Iracilda Zeppone, Therapeutic and Prophylactic Tools for Sporotrichosis: Current Strategies and Future Tendencies, in Sporotrichosis, 2015. Crossref

  11. Gamazo Carlos, Irache Juan M., Antigen Delivery Systems as Oral Adjuvants, in Molecular Vaccines, 2014. Crossref

  12. Epand R. F., Sarig H., Ohana D., Papahadjopoulos-Sternberg B., Mor A., Epand R. M., Physical Properties Affecting Cochleate Formation and Morphology Using Antimicrobial Oligo-acyl-lysyl Peptide Mimetics and Mixtures Mimicking the Composition of Bacterial Membranes in the Absence of Divalent Cations, The Journal of Physical Chemistry B, 115, 10, 2011. Crossref

  13. Nagarsekar Kalpa, Ashtikar Mukul, Thamm Jana, Steiniger Frank, Schacher Felix, Fahr Alfred, May Sylvio, Electron Microscopy and Theoretical Modeling of Cochleates, Langmuir, 30, 44, 2014. Crossref

  14. Hudiyanti D, Al-Khafiz M F, Anam K, Encapsulation of cinnamic acid and galangal extracts in coconut (Cocos nucifera L.) liposomes, Journal of Physics: Conference Series, 1442, 1, 2020. Crossref

  15. Lipa-Castro Antonio, Legrand François-Xavier, Barratt Gillian, Cochleate drug delivery systems: An approach to their characterization, International Journal of Pharmaceutics, 610, 2021. Crossref

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