Library Subscription: Guest
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections
Critical Reviews™ in Therapeutic Drug Carrier Systems
IF: 2.9 5-Year IF: 3.72 SJR: 0.736 SNIP: 0.818 CiteScore™: 4.6

ISSN Print: 0743-4863
ISSN Online: 2162-660X

Volumes:
Volume 37, 2020 Volume 36, 2019 Volume 35, 2018 Volume 34, 2017 Volume 33, 2016 Volume 32, 2015 Volume 31, 2014 Volume 30, 2013 Volume 29, 2012 Volume 28, 2011 Volume 27, 2010 Volume 26, 2009 Volume 25, 2008 Volume 24, 2007 Volume 23, 2006 Volume 22, 2005 Volume 21, 2004 Volume 20, 2003 Volume 19, 2002 Volume 18, 2001 Volume 17, 2000 Volume 16, 1999 Volume 15, 1998 Volume 14, 1997 Volume 13, 1996 Volume 12, 1995

Critical Reviews™ in Therapeutic Drug Carrier Systems

DOI: 10.1615/CritRevTherDrugCarrierSyst.v16.i5.20
62 pages

Microemulsions: An Overview and Pharmaceutical Applications

Srini Tenjarla
Associate Director, Shire Pharmaceutical Development Inc, 1901, Research Boulevard, Suite 500, Rockville, MD 20850; and Serquest, a Southern Research Institute Company, 2000 Ninth Avenue South, Birmingham, AL 35205, USA

ABSTRACT

Microemulsions are potential drug carrier systems for oral, topical, and parenteral administration. They offer the advantage of spontaneous formation, ease of manufacturing and scale-up, thermodynamic stability, and improved drug solubilization and bioavailability. Preparing a pharmaceutically acceptable dosage form demands a clear understanding of the micro-emulsion structure, phase behavior, factors leading to its thermodynamic stability, factors influencing drug release from the formulation, requirements of ideal microemulsion excipients, and the potential uses and limitations of the microemulsion system. Knowledge of the various methods available to thoroughly characterize a microemulsion system is essential. An overview of these factors is presented in this review. While microemulsion is used in several fields, in this review the pharmaceutical applications are emphasized. Several references are cited, but the list is by no means exhaustive. The review is written so that a newcomer to the field can easily grasp the important facts pertaining to this novel delivery system.


Articles with similar content:

Floating Dosage Systems in Drug Delivery
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.19, 2002, issue 6
L. Hari Vardhan Reddy, R. S. R. Murthy
Enhancement of Transdermal Delivery of Heparin by Various Physical and Chemical Enhancement Techniques
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.26, 2009, issue 6
S. S. Lanke, Ajay K. Banga, J. G. Strom
Gastric Retentive Dosage Forms: A Review
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.20, 2003, issue 6
Verne E. Cowles, Bret Berner, Sui Yuen Eddie Hou
Exploiting the Tumor Phenotype Using Biodegradable Submicron Carriers of Chemotherapeutic Drugs
Critical Reviews™ in Oncogenesis, Vol.19, 2014, issue 3-4
Aliasger K. Salem, Sean M. Geary
Herbal Medicines in Neurodegenerative Disorders: An Evolutionary Approach through Novel Drug Delivery System
Journal of Environmental Pathology, Toxicology and Oncology, Vol.37, 2018, issue 3
Sunil Kumar Dubey, Gaurav Gupta, Ranendra Narayan Saha, Kowthavarapu Venkata Krishna, Gautam Singhvi, Tejas Agnihotri