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Critical Reviews™ in Immunology

Published 6 issues per year

ISSN Print: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Understanding Lung Immunopathology Caused by the Human Metapneumovirus: Implications for Rational Vaccine Design

Volume 35, Issue 3, 2015, pp. 185-202
DOI: 10.1615/CritRevImmunol.2015013844
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ABSTRACT

Acute respiratory tract infections (ARTIs) are the major cause of child mortality worldwide. The human metapneumovirus (hMPV) is one of the leading causes of child hospitalizations due to pneumonia. The adaptive immune response generated by the host against hMPV is usually inefficient at protecting from reinfections, which is repeat throughout life, from childhood to old age. Despite considerable research efforts, to date there are no licensed vaccines to prevent respiratory disease caused by hMPV infection. In this article we review current vaccine strategies tested in animal models and the implication of such studies in understanding the different immune cell populations that contribute to hMPV clearance and the prevention and resolution of lung inflammation upon exposure to the virus.

CITED BY
  1. Quinton Lee J., Walkey Allan J., Mizgerd Joseph P., Integrative Physiology of Pneumonia, Physiological Reviews, 98, 3, 2018. Crossref

  2. González Liliana A., Vázquez Yaneisi, Mora Jorge E., Palavecino Christian E., Bertrand Pablo, Ferrés Marcela, Contreras Ana M., Beckhaus Andrea A., Riedel Claudia A., Bueno Susan M., Evaluation of monoclonal antibodies that detect conserved proteins from Respiratory Syncytial Virus, Metapneumovirus and Adenovirus in human samples, Journal of Virological Methods, 254, 2018. Crossref

  3. Mizgerd Joseph P., Inflammation and Pneumonia, Clinics in Chest Medicine, 39, 4, 2018. Crossref

  4. Soto Jorge A., Gálvez Nicolas M. S., Andrade Catalina A., Pacheco Gaspar A., Bohmwald Karen, Berrios Roslye V., Bueno Susan M., Kalergis Alexis M., The Role of Dendritic Cells During Infections Caused by Highly Prevalent Viruses, Frontiers in Immunology, 11, 2020. Crossref

  5. Gálvez Nicolás M. S., Andrade Catalina A., Pacheco Gaspar A., Soto Jorge A., Stranger Vicente, Rivera Thomas, Vásquez Abel E., Kalergis Alexis M., Host Components That Modulate the Disease Caused by hMPV, Viruses, 13, 3, 2021. Crossref

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