Published 6 issues per year
ISSN Print: 1040-8401
ISSN Online: 2162-6472
Indexed in
The Phenotype and Function of Lung Dendritic Cells
ABSTRACT
Dendritic cells (DCs) are central to the integration of innate and adaptive immunity. In contrast to B and T lymphocytes, DCs have retained many of the pattern recognition receptors and are thus uniquely able to sense stimuli such as tissue damage, necrosis, and bacterial and viral infection. Also, immature DCs respond to danger signals in the environment, which leads to their maturation, upon which DCs differentiate and acquire the ability to direct the development of the primary immune response. The ability of lung DCs to elicit specific CD4 and CD8 T lymphocyte responses have made them attractive targets for vaccine development strategies in the treatment and prevention of diseases such as allograft rejection responses, allergy, and asthma, as well as autoimmune disease and cancer.
-
Bueno Susan M., Riquelme Sebastián, Riedel Claudia A., Kalergis Alexis M., Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity, Immunology, 137, 1, 2012. Crossref
-
Givi Masoumeh E., Peck Michael J., Boon Louis, Mortaz Esmaeil, The role of dendritic cells in the pathogenesis of cigarette smoke-induced emphysema in mice, European Journal of Pharmacology, 721, 1-3, 2013. Crossref
-
Langhoff Erik, Siegel Robert E., Pneumonitis in human cytomegalovirus infection, Current Infectious Disease Reports, 8, 3, 2006. Crossref
-
Awasthi Shanjana, Wolf Roman, White Gary, Ontogeny and phagocytic function of baboon lung dendritic cells, Immunology & Cell Biology, 87, 5, 2009. Crossref
-
Mathieu C., Gale E. A. M., Inhaled insulin: gone with the wind?, Diabetologia, 51, 1, 2007. Crossref
-
Johnson Kirby L., Stroh Helene, Tadesse Serkalem, Norwitz Errol R., Richey Lauren, Kallenbach Lisa R., Bianchi Diana W., Fetal Cells in the Murine Maternal Lung Have Well-Defined Characteristics and Are Preferentially Located in Alveolar Septum, Stem Cells and Development, 21, 1, 2012. Crossref
-
Gafa Valérie, Remoli Maria Elena, Giacomini Elena, Gagliardi Maria Cristina, Lande Roberto, Severa Martina, Grillot Renée, Coccia Eliana M., In vitro infection of human dendritic cells by Aspergillus fumigatus conidia triggers the secretion of chemokines for neutrophil and Th1 lymphocyte recruitment, Microbes and Infection, 9, 8, 2007. Crossref
-
Awasthi Shanjana, Madhusoodhanan Rakhesh, Wolf Roman, Surfactant protein-A and toll-like receptor-4 modulate immune functions of preterm baboon lung dendritic cell precursor cells, Cellular Immunology, 268, 2, 2011. Crossref
-
Getting Stephen J., Riffo-Vasquez Yanira, Pitchford Simon, Kaneva Magdalena, Grieco Paolo, Page Clive P., Perretti Mauro, Spina Domenico, A role for MC3R in modulating lung inflammation, Pulmonary Pharmacology & Therapeutics, 21, 6, 2008. Crossref
-
Whale Tyler A., Griebel Philip J., A sheep in wolf’s clothes: Can neutrophils direct the immune response?, The Veterinary Journal, 180, 2, 2009. Crossref
-
Hong Li, Webb Tonya J., Wilkes David S., Dendritic cell–T cell interactions: CD8αα expressed on dendritic cells regulates T cell proliferation, Immunology Letters, 108, 2, 2007. Crossref
-
Jose Purnima, Avdiushko Margarita G., Akira Shizuo, Kaplan Alan M., Cohen Donald A., INHIBITION OF INTERLEUKIN-10 SIGNALING IN LUNG DENDRITIC CELLS BY TOLL-LIKE RECEPTOR 4 LIGANDS, Experimental Lung Research, 35, 1, 2009. Crossref
-
Bondue Benjamin, Vosters Olivier, de Nadai Patricia, Glineur Stéphanie, De Henau Olivier, Luangsay Souphalone, Van Gool Frédéric, Communi David, De Vuyst Paul, Desmecht Daniel, Parmentier Marc, Ross Susan R., ChemR23 Dampens Lung Inflammation and Enhances Anti-viral Immunity in a Mouse Model of Acute Viral Pneumonia, PLoS Pathogens, 7, 11, 2011. Crossref
-
Smit Joost J., Lindell Dennis M., Boon Louis, Kool Mirjam, Lambrecht Bart N., Lukacs Nicholas W., Bozza Patricia, The Balance between Plasmacytoid DC versus Conventional DC Determines Pulmonary Immunity to Virus Infections, PLoS ONE, 3, 3, 2008. Crossref
-
Inchley Christopher S, Sonerud Tonje, Fjærli Hans O, Nakstad Britt, Reduced Dicer expression in the cord blood of infants admitted with severe respiratory syncytial virus disease, BMC Infectious Diseases, 11, 1, 2011. Crossref
-
Ptaschinski Catherine, Lukacs Nicholas W., Early Life Respiratory Syncytial Virus Infection and Asthmatic Responses, Immunology and Allergy Clinics of North America, 39, 3, 2019. Crossref
-
Liu Suna, Hao Changfu, Bao Lei, Zhao Dehua, Zhang Hongyi, Hou Jianyong, Wang Di, Chen Huiting, Feng Feifei, Yao Wu, Silica Particles Mediate Phenotypic and Functional Alteration of Dendritic Cells and Induce Th2 Cell Polarization, Frontiers in Immunology, 10, 2019. Crossref
-
Thanki Kaushik, Blum Kevin G, Thakur Aneesh, Rose Fabrice, Foged Camilla, Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities, Therapeutic Delivery, 9, 10, 2018. Crossref
-
Benson Heather L, Suzuki Hidemi, Lott Jeremy, Fisher Amanda Jo, Walline Crystal, Heidler Kathleen M, Brutkiewicz Randy, Blum Janice S, Wilkes David S, Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production, Respiratory Research, 13, 1, 2012. Crossref
-
Krause Anja, Xu Yaqin, Ross Sara, Wu Wendy, Joh Ju, Worgall Stefan, Absence of vaccine-enhanced RSV disease and changes in pulmonary dendritic cells with adenovirus-based RSV vaccine, Virology Journal, 8, 1, 2011. Crossref
-
Hansen Soren, Lo Bernice, Evans Kathy, Neophytou Pavlos, Holmskov Uffe, Wright Jo Rae, Surfactant Protein D Augments Bacterial Association but Attenuates Major Histocompatibility Complex Class II Presentation of Bacterial Antigens, American Journal of Respiratory Cell and Molecular Biology, 36, 1, 2007. Crossref
-
Xu Yaqin, Krause Anja, Limberis Maria, Worgall Tilla S., Worgall Stefan, Low Sphingosine-1–Phosphate Impairs Lung Dendritic Cells in Cystic Fibrosis, American Journal of Respiratory Cell and Molecular Biology, 48, 2, 2013. Crossref
-
Beamer Celine A, Holian Andrij, Antigen-Presenting Cell Population Dynamics during Murine Silicosis, American Journal of Respiratory Cell and Molecular Biology, 37, 6, 2007. Crossref