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Critical Reviews™ in Immunology

Published 6 issues per year

ISSN Print: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

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Role of p53 in Systemic Autoimmune Diseases

Volume 34, Issue 6, 2014, pp. 509-516
DOI: 10.1615/CritRevImmunol.2014012193
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ABSTRACT

The tumor suppressor p53 has been shown to play a central role in tumor suppression by inducing apoptosis, cell cycle arrest, senescence, and DNA repair. In addition, recent observations indicate that the dysfunction of p53 is associated with the development of autoimmune diseases. In this review, we discuss the importance of p53 in various human and murine autoimmune diseases. We also discuss the role of p53 in controlling the balance between Th17 cells and Tregs, the alteration of which is shown to be involved in the development of autoimmunity. It is postulated that the selective restoration of p53 function in T cells could be applicable to the treatment of systemic autoimmune diseases.

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  3. Choubey Divaker, Panchanathan Ravichandran, Absent in Melanoma 2 proteins in SLE, Clinical Immunology, 176, 2017. Crossref

  4. Yang Jie, Zhu Ji-min, Wu Song, Li Jing, Wang Ming-rui, Wang Ting-ting, Lu Yu-wei, Association study between the TP53 Rs1042522G/C polymorphism and susceptibility to systemic lupus erythematosus in a Chinese Han population, Rheumatology International, 37, 4, 2017. Crossref

  5. Ting Sze-Wen, Yang Shih-Jyun, Lee Yung-Yi, Atypical fibroxanthoma in a young female patient with systemic lupus erythematosus: A case report and literature review, Dermatologica Sinica, 36, 4, 2018. Crossref

  6. Zhou Yan, Leng Xiao, He Yan, Li Yan, Liu Yuan, Liu Yang, Zou Qiang, Shi Guixiu, Wang Yantang, Loss of Perp in T Cells Promotes Resistance to Apoptosis of T Helper 17 Cells and Exacerbates the Development of Experimental Autoimmune Encephalomyelitis in Mice, Frontiers in Immunology, 9, 2018. Crossref

  7. Takami Mariko, Cunha Christina, Motohashi Shinichiro, Nakayama Toshinori, Iwashima Makio, TGF‐β suppresses RasGRP1 expression and supports regulatory T cell resistance against p53‐induced CD28‐dependent T‐cell apoptosis, European Journal of Immunology, 48, 12, 2018. Crossref

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  10. Pellegrino Marsha, Traversi Gianandrea, Arena Andrea, Cappa Marco, Rosado M. Manuela, Andreani Marco, Delfino Domenico V., Moretti Fabiola, Fierabracci Alessandra, Seo Keun Seok, Effect of p53 activation through targeting MDM2/MDM4 heterodimer on T regulatory and effector cells in the peripheral blood of Type 1 diabetes patients, PLOS ONE, 15, 1, 2020. Crossref

  11. Yajima Satoshi, Suzuki Takashi, Oshima Yoko, Shiratori Fumiaki, Funahashi Kimihiko, Kawai Shinichi, Nanki Toshihiro, Muraoka Sei, Urita Yoshihisa, Saida Yoshihisa, Okazumi Shinichi, Kitagawa Yuko, Hirata Yuki, Hasegawa Hirotoshi, Okabayashi Koji, Murakami Masahiko, Yamashita Takeshi, Kato Rei, Matsubara Hisahiro, Murakami Kentaro, Nakajima Yasuaki, Sugita Hironobu, Klammer Martin, Shimada Hideaki, New Assay System Elecsys Anti-p53 to Detect Serum Anti-p53 Antibodies in Esophageal Cancer Patients and Colorectal Cancer Patients: Multi-institutional Study, Annals of Surgical Oncology, 28, 7, 2021. Crossref

  12. Li Jian-Ping, Li Rui, Liu Xiao, Huo Chen, Liu Ting-Ting, Yao Jie, Qu Yi-Qing, A Seven Immune-Related lncRNAs Model to Increase the Predicted Value of Lung Adenocarcinoma, Frontiers in Oncology, 10, 2020. Crossref

  13. Hua Juan, Chen Yan, Fu Bin, Chen Xu, Xu Xue-jun, Yang Shuang-Hui, Chen Cong, Xu Ya-jing, Downregulation of p53 by Insufficient CTCF in CD4+ T Cells Is an Important Factor Inducing Acute Graft-Versus-Host Disease, Frontiers in Immunology, 11, 2020. Crossref

  14. Wiatrek Dagmara M., Candela Maria E., Sedmík Jiří, Oppelt Jan, Keegan Liam P., O'Connell Mary A., Activation of innate immunity by mitochondrial dsRNA in mouse cells lacking p53 protein, RNA, 25, 6, 2019. Crossref

  15. Arena Andrea, Stigliano Antonio, Belcastro Eugenia, Giorda Ezio, Rosado Maria Manuela, Grossi Armando, Assenza Maria Rita, Moretti Fabiola, Fierabracci Alessandra, p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity, Frontiers in Immunology, 12, 2021. Crossref

  16. Tutino Marco, Mattei Giorgia, Paoloni Niccolò, Santolamazza Valentina, Corporate governance, CSR and financial performances: What types of relationships exist between these dimensions?, Corporate governance: Search for the advanced practices, 2019. Crossref

  17. Słomiński Bartosz, Skrzypkowska Maria, Ryba-Stanisławowska Monika, Myśliwiec Małgorzata, Trzonkowski Piotr, Associations of TP53 codon 72 polymorphism with complications and comorbidities in patients with type 1 diabetes, Journal of Molecular Medicine, 99, 5, 2021. Crossref

  18. Seki Scott M., Posyniak Kacper, McCloud Rebecca, Rosen Dorian A., Fernández-Castañeda Anthony, Beiter Rebecca M., Serbulea Vlad, Nanziri Sarah C., Hayes Nikolas, Spivey Charles, Gemta Lelisa, Bullock Timothy N. J., Hsu Ku-Lung, Gaultier Alban, Modulation of PKM activity affects the differentiation of T H 17 cells , Science Signaling, 13, 655, 2020. Crossref

  19. Kung Che-Pei, Weber Jason D., It’s Getting Complicated—A Fresh Look at p53-MDM2-ARF Triangle in Tumorigenesis and Cancer Therapy, Frontiers in Cell and Developmental Biology, 10, 2022. Crossref

  20. Yoon Kyoung Wan, Byun Sanguine, Kwon Eunjeong, Hwang So-Young, Chu Kiki, Hiraki Masatsugu, Jo Seung-Hee, Weins Astrid, Hakroush Samy, Cebulla Angelika, Sykes David B., Greka Anna, Mundel Peter, Fisher David E., Mandinova Anna, Lee Sam W., Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53, Science, 349, 6247, 2015. Crossref

  21. Gansmo Liv B., Lie Benedicte A., Mæhlen Marthe T., Vatten Lars, Romundstad Pål, Hveem Kristian, Lønning Per E., Knappskog Stian, Polymorphisms in the TP53-MDM2-MDM4-axis in patients with rheumatoid arthritis, Gene, 793, 2021. Crossref

  22. Cui Jiajia, Li Hui, Wang Tianling, Shen Qin, Yang Yuanhao, Yu Xiujuan, Hu Huaixia, Novel Immune-Related Genetic Expression for Primary Sjögren's Syndrome, Frontiers in Medicine, 8, 2022. Crossref

  23. Huang Feng-Jiao, Liu Yan-Ling, Wang Jiao, Zhou Ying-Ying, Zhao Shui-Ying, Qin Gui-Jun, LncRNA RUNX1-IT1 affects the differentiation of Th1 cells by regulating NrCAM transcription in Graves’ disease, Cell Cycle, 21, 9, 2022. Crossref

  24. Zhao Ting, Yang Qi, Xi Yujiang, Xie Zhaohu, Shen Jiayan, Li Zhenmin, Li Zhaofu, Qin Dongdong, Ferroptosis in Rheumatoid Arthritis: A Potential Therapeutic Strategy, Frontiers in Immunology, 13, 2022. Crossref

  25. Muñoz-Fontela César, Mandinova Anna, Aaronson Stuart A., Lee Sam W., Emerging roles of p53 and other tumour-suppressor genes in immune regulation, Nature Reviews Immunology, 16, 12, 2016. Crossref

  26. Oktem Elif Kubat, Yazar Metin, Drug Repositioning Identifies Six Drug Candidates for Systemic Autoimmune Diseases by Integrative Analyses of Transcriptomes from Scleroderma, Systemic Lupus Erythematosus, and Sjogren's Syndrome, OMICS: A Journal of Integrative Biology, 26, 12, 2022. Crossref

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