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Critical Reviews™ in Immunology

Published 6 issues per year

ISSN Print: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Viral Mechanisms Involved in the Transcriptional CBP/р300 Regulation of Inflammatory and Immune Responses

Volume 29, Issue 2, 2009, pp. 131-154
DOI: 10.1615/CritRevImmunol.v29.i2.30
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ABSTRACT

The transcriptional coactivators CREB-binding protein (СВР) and р300 regulate inducible transcription in multiple cellular processes and during the establishment of inflammatory and immune response. These closely related transcriptional coactivators arc able to modulate the transcription of specific genes, modify chromatin structure, and influence cell-cycle progression. Several viruses have been shown to interfere with CREB-binding protein/р300 function, modulating their transcriptional activity. During a viral infection, reprogramming of the host cell gene expression pattern is required to establish an adequate antiviral response and, thus, many viruses encode proteins that can influence or interfere with cellular signals to evade inflammation and immune response. The mechanism of transcriptional regulation by coactivator proteins, including р300/CBP, has been the focus of intense study. As a part of this, some of the molecular instruments developed by viruses to counteract the host response and their role in the regulation of inflammation and immune response are summarized in this review.

KEY WORDS: CBP/p300, NF-κ, В, , NFAT, COX-2, TNF-α, , iNOS, A238L
CITED BY
  1. Li Pingping, Fan WuQiang, Xu Jianfeng, Lu Min, Yamamoto Hiroyasu, Auwerx Johan, Sears Dorothy D., Talukdar Saswata, Oh DaYoung, Chen Ai, Bandyopadhyay Gautam, Scadeng Miriam, Ofrecio Jachelle M., Nalbandian Sarah, Olefsky Jerrold M., Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity, Cell, 147, 4, 2011. Crossref

  2. Sandoval J., Pereda J., Rodriguez J. L., Escobar J., Hidalgo J., Joosten L. A. B., Franco L., Sastre J., López-Rodas G., Ordered transcriptional factor recruitment and epigenetic regulation of tnf-α in necrotizing acute pancreatitis, Cellular and Molecular Life Sciences, 67, 10, 2010. Crossref

  3. Dosztanyi Z., Meszaros B., Simon I., Bioinformatical approaches to characterize intrinsically disordered/unstructured proteins, Briefings in Bioinformatics, 11, 2, 2010. Crossref

  4. de Paiva e Almeida Sílvia Cristina, de Oliveira Vivian Leite, Parkhouse Robert Michael Evans, Impact on antibody responses of B-cell-restricted transgenic expression of a viral gene inhibiting activation of NF-κB and NFAT, Archives of Virology, 160, 6, 2015. Crossref

  5. Moustakim Moses, Clark Peter G. K., Hay Duncan A., Dixon Darren J., Brennan Paul E., Chemical probes and inhibitors of bromodomains outside the BET family, MedChemComm, 7, 12, 2016. Crossref

  6. Zakaryan Hovakim, Revilla Yolanda, African swine fever virus: current state and future perspectives in vaccine and antiviral research, Veterinary Microbiology, 185, 2016. Crossref

  7. Zaware Nilesh, Zhou Ming-Ming, Chemical modulators for epigenome reader domains as emerging epigenetic therapies for cancer and inflammation, Current Opinion in Chemical Biology, 39, 2017. Crossref

  8. Bekesi Angela, Abdellaoui Sara, Holroyd Natalie, Van Delm Wouter, Pardon Els, Pauwels Jarne, Gevaert Kris, Steyaert Jan, Derveaux Stefaan, Borysik Antoni, Tompa Peter, Challenges in the Structural–Functional Characterization of Multidomain, Partially Disordered Proteins CBP and p300: Preparing Native Proteins and Developing Nanobody Tools, in Intrinsically Disordered Proteins, 611, 2018. Crossref

  9. Donner Amy, King Heather, Brennan Paul E., Moustakim Moses, Zuercher William J., Chemical Probes, in Epigenetic Drug Discovery, 2019. Crossref

  10. Villanueva-Cañas José Luis, Horvath Vivien, Aguilera Laura, González Josefa, Diverse families of transposable elements affect the transcriptional regulation of stress-response genes in Drosophila melanogaster, Nucleic Acids Research, 2019. Crossref

  11. Chen Yan, Huang Bin, Zhao Yan, Qi Di, Wang Daoxin, Increased p300/CBP expression in acute respiratory distress syndrome is associated with interleukin‐17 and prognosis, The Clinical Respiratory Journal, 2020. Crossref

  12. Kim Jung-Yeon, Jo Jungmin, Leem Jaechan, Park Kwan-Kyu, Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice, Antioxidants, 9, 12, 2020. Crossref

  13. Dong Qian, Dunkelberger Jenelle, Lim Kyu-Sang, Lunney Joan K, Tuggle Christopher K, Rowland Raymond R R, Dekkers Jack C M, Associations of natural variation in the CD163 and other candidate genes on host response of nursery pigs to porcine reproductive and respiratory syndrome virus infection, Journal of Animal Science, 99, 10, 2021. Crossref

  14. Amarante Anderson de Mendonça, da Silva Isabel Caetano de Abreu, Carneiro Vitor Coutinho, Vicentino Amanda Roberta Revoredo, Pinto Marcia de Amorim, Higa Luiza Mendonça, Moharana Kanhu Charan, Talyuli Octavio A. C., Venancio Thiago Motta, de Oliveira Pedro Lagerblad, Fantappié Marcelo Rosado, Rasgon Jason L., Zika virus infection drives epigenetic modulation of immunity by the histone acetyltransferase CBP of Aedes aegypti, PLOS Neglected Tropical Diseases, 16, 6, 2022. Crossref

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