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Journal of Long-Term Effects of Medical Implants

Published 4 issues per year

ISSN Print: 1050-6934

ISSN Online: 1940-4379

SJR: 0.184 SNIP: 0.485 CiteScore™:: 1.1 H-Index: 39

Indexed in

An Atypical Immune-Inflammatory Disorder Secondary to Breast Implant Exposure

Volume 22, Issue 1, 2012, pp. 33-48
DOI: 10.1615/JLongTermEffMedImplants.v22.i1.50
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ABSTRACT

Objective: The objectives of this investigation were to determine a diagnosis and identify the underlying etiology. Case presentation: A 71-year-old female had experienced a constellation of symptoms stemming from the 1980s, including the following types: neurological, respiratory, gastroenterological, dermatological, skeletal, and ophthalmological. No correlation with an environmental (or other) factor could be found to account for the presence or exacerbation of unexplained signs and symptoms-except that the patient had been exposed to a series of silicone breast implants. Anatomical diagnosis: An atypical immune-inflammatory disorder caused by an originally exogenous noninfectious agent, i.e., breast prostheses, and diagnosed as prosthetic mammoplasty sensitivity syndrome (PMSS). Significance: This case study underscores the risks of breast implantation using prosthetic devices. It shows the potential for adverse health effects following breast implantation in humans. It highlights the impact of social factors that has adversely affected the medical treatment of this subgroup of patients, and documents postimplantation psychiatric morbidity attributable in part to adverse physical health effects from exposure to breast implants. Relevance to clinical practice: Patients that present with symptoms, have a history of breast implants, and no firm diagnosis of disease or disorder etiology attributable to their clinical signs and symptoms, laboratory, and/or imaging results must be considered for PMSS.

CITED BY
  1. Alonso Ricardo, Rey Raúl, Garcea Orlando, Encefalomielitis aguda diseminada en adultos: presentación de una serie de casos en Argentina, Neurología Argentina, 6, 2, 2014. Crossref

  2. Cohen Tervaert Jan Willem, Colaris Maartje J., van der Hulst René R., Silicone breast implants and autoimmune rheumatic diseases: myth or reality, Current Opinion in Rheumatology, 29, 4, 2017. Crossref

  3. Cohen Tervaert Jan Willem, Silicone, in Mosaic of Autoimmunity, 2019. Crossref

  4. Hallab Nadim James, Samelko Lauryn, Hammond Dennis, The Inflammatory Effects of Breast Implant Particulate Shedding: Comparison With Orthopedic Implants, Aesthetic Surgery Journal, 39, Supplement_1, 2019. Crossref

  5. Cohen Tervaert JW, Mohazab N, Redmond D, van Eeden C, Osman M., Breast implant illness: scientific evidence of its existence, Expert Review of Clinical Immunology, 18, 1, 2022. Crossref

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