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Journal of Environmental Pathology, Toxicology and Oncology
IF: 1.241 5-Year IF: 1.349 SJR: 0.356 SNIP: 0.613 CiteScore™: 1.61

ISSN Print: 0731-8898
ISSN Online: 2162-6537

Journal of Environmental Pathology, Toxicology and Oncology

DOI: 10.1615/JEnvironPatholToxicolOncol.2016016379
pages 375-386

Effect of Prenatal Exposure to Pesticides on Children's Health

Magdalena Matysiak
Department of Molecular Biology and Translational Research, Institute of Rural Health, Lublin, Poland
Marcin Kruszewski
Department of Molecular Biology and Translational Research, Institute of Rural Health, Lublin, Poland; Centre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Warsaw, Poland
Barbara Jodlowska-Jedrych
Department of Histology and Embryology with Experimental Cytology Unit, Medical University of Lublin, Lublin, Poland
Lucyna Kapka-Skrzypczak
Department of Molecular Biology and Translational Research, Institute of Rural Health, Lublin, Poland

ABSTRACT

The aim of this study was to summarize the current state of knowledge on pesticide-related fertility problems and disadventeges of childrens due to prenatal pesticides exposure. Available literature was analyzed. Due to the extent of the issue, the study focuses on epidemiological studies conducted in humans, despite evidence from in vitro and animal studies. It seems certain that exposure to harmful chemicals is one of the factors that may cause a decline in fertility and problems with conceiving, whereas exposure during pregnancy can impair foetal development. Prenatal exposure may also result in the occurrence of childhood cancer and neurobehavioral disorders. The meaning of the project is to summarize the role of pesticides in the process of reproduction. This applies especially to people working in agriculture, since they might be occupationally exposed to pesticides.