Begell House Inc.
Journal of Long-Term Effects of Medical Implants
JLT
1050-6934
12
1
2002
GUEST EDITORIAL: A Tribute to Richard F. Ediich, M.D., Ph.D., Editor-in-Chief Journal of Long-Term Effects of Medical Implants
4
10.1615/JLongTermEffMedImplants.v12.i1.10
William C.
Lineaweaver
Division of Plastic Surgery. The University of Mississippi Medical Center, 2500, North State Street, Jackson, MS 39216-4505
Richard
Edlich
Legacy Verified Level I Shock Trauma Center Pediatrics and Adults, Legacy Emanual Hospital; and Plastic Surgery, Biomedical Engineering and Emergency Medicine, University of Virginia Health System, USA
A Personal Perspective from a Student, Colleague, and Friend
Recent Advances in Tissue Engineering: An Invited Review
33
10.1615/JLongTermEffMedImplants.v12.i1.20
R. G.
Pearson
Tissue Engineering Group, School of Pharmaceutical Sciences, The University of Nottingham, NG7 2RD, UK
R.
Bhandari
Tissue Engineering Group, School of Pharmaceutical Sciences, The University of Nottingham, NG7 2RD, UK
R. A.
Quirk
RegenTec Ltd., 1 Faraday Building, Science & Technology Park, Nottingham, NG7 2QP, UK
Kevin M.
Shakesheff
EPSRC Advanced Fellow. Tissue Engineering Group School of Pharmaceutical Sciences The University of Nottingham Nottingham NG7 2RD United Kingdom
Tissue formation within the body, as part of a development or repair process, is a complex event in which cell populations self-assemble into functional units. There is intense academic, medical, and commercial interest in finding methods of replicating these events outside the body. This interest has accelerated with the demonstration of the engineering of skin and cartilage tissue in the laboratory and there is now worldwide activity in the in vitro regeneration of tissues including nerve, liver, bone, heart valves, blood vessels, bladder, and kidney. Approaches to tissue engineering center on the need to provide signals to cell populations to promote cell proliferation and differentiation. This review considers recent advances in methods of providing these signals to cells using examples of progress in the engineering of complex tissues.
A Long-Term Clinical Study on Dislocated Ankle Fractures Fixed with Self-Reinforced Polylevolactide (SR-PLLA) Implants
18
10.1615/JLongTermEffMedImplants.v12.i1.30
Nina H.
Voutilainen
Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, FIN-00260 Helsinki, Finland
Michael W.
Hess
Electron Microscopy Unit, Institute of Biotechnology, University of Helsinki, Finland
Terttu S.
Toivonen
Department of Pathology, Maria Hospital, Helsinki, Finland
Leena A.
Krogerus
Department of Pathology, Maria Hospital, Helsinki, Finland
Esa K.
Partio
Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, FIN-00260 Helsinki, Finland
Hannu V. J.
Patiala
Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, FIN-00260 Helsinki, Finland
Sixteen patients with dislocated ankle fractures fixed between 1988 and 1991 with self-reinforced poly(L-lactide; SR-PLLA) screws and/or rods were followed up after 8.6 to 11.7 years (mean 9.6 years) at the Department of Orthopaedics and Traumatology, Helsinki University Central Hospital. In all patients accurate reduction of the fractures was retained and uneventful bony union was achieved. Good or excellent long-term functional results were observed in 15 out of 16 patients. One patient had post-traumatic osteoarthritis. In 5 patients, a late tissue reaction was observed over an extruding screw head with mild symptoms, which led to removal of small palpable masses. There were two superficial wound infections, one after a primary operation and one caused by a late tissue reaction after an operation. The correct operative technique, where all extruding extraosseous SR-PLLA material should be removed during the primary operation, should be followed.
Frictional Torque and Wear of Retrieved Hip Prostheses: A Comparison Between Alumina/PE and Co-Cr/PE Prostheses
10
10.1615/JLongTermEffMedImplants.v12.i1.40
Atsushi
Kusaba
Department of Orthopaedic Surgery, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-Ku, Yokohama, Kanagawa 227-8501 Japan
Yoshikatsu
Kuroki
Department of Orthopaedic Surgery, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-Ku, Yokohama, Kanagawa 227-8501 Japan
Saiji
Kondo
Institute for Joint Replacement and Rheumatology, Zama General Hospital, 1-50-1 Sobudai, Zama, Kanagawa 2520011, Japan
Isao
Hirose
Department of Orthopaedic Surgery, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-Ku, Yokohama, Kanagawa 227-8501 Japan
Yuichi
Ito
Department of Orthopaedic Surgery, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-Ku, Yokohama, Kanagawa 227-8501 Japan
Yoshio
Shirasaki
Department of Biomechanics, National Engineering Laboratory, 1-2 Namiki, Tsukuba, Ibaragi 305-8504 Japan
Tetsuta
Tateishi
Department of Biomechanics, National Engineering Laboratory, 1-2 Namiki, Tsukuba, Ibaragi 305-8504 Japan
Jorg
Scholz
Department of Orthopaedic Surgery, Auguste-Viktoria Hospital, 125 Rubensstrasse, D-12157 Berlin, Germany
Frictional torque and wear were measured in 67 retrieved cups with internal diameters of 32 mm. Thirty cups were combined with alumina heads and 37 were combined with metal heads. A lower prevalence of cup loosening was observed in alumina-polyethylene implants than in metal-polyethylene implants. No relation between frictional torque and stability of implants was detected for either type, whereas retrieved cups of alumina—polyethylene implants showed lower frictional torque than those of metal-polyethylene implants. Less wear was observed in the cups of alumina-polyethylene implants (0.13 mm/y) than in those of metal—polyethylene implants (0.19 mm/y). Less wear was observed in cups without loosening than in those with loosening in both types. These results suggest that wear has a greater influence on the stability of cups than frictional torque.