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International Journal of Medicinal Mushrooms

Publication de 12  numéros par an

ISSN Imprimer: 1521-9437

ISSN En ligne: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Lanostane-Type Triterpenes and Abietane-Type Diterpene from the Sclerotia of Chaga Medicinal Mushroom, Inonotus obliquus (Agaricomycetes), and Their Biological Activities

Volume 20, Numéro 6, 2018, pp. 507-516
DOI: 10.1615/IntJMedMushrooms.2018026007
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RÉSUMÉ

Three new lanostane-type triterpenes (compounds 1-3), 1 new abietane-type diterpene (compound 4), and 10 known compounds (5-14) were isolated from sclerotia of Inonotus obliquus. Their structures were elucidated through a combination of spectrometric techniques, including infrared, 1-dimensional, and 2-dimensional nuclear magnetic resonance and high-resolution electrospray mass spectrometry. In in vitro assays, compounds 2 and 4-12 showed hepatoprotective effects against D-galactosamine-induced damage in WB-F344 cells, with inhibitory effects from 35.4% to 83.8%. Compounds 3, 13, and 14 exhibited selective cytotoxicity against Bel-7402, A-549, or KB cell lines. Compounds 13 and 14 showed inhibitory effects against protein tyrosine kinases, with half-maximal inhibitory concentrations of 23.8 and 7.4 μmol/L, respectively.

CITÉ PAR
  1. Gründemann Carsten, Reinhardt Jakob K., Lindequist Ulrike, European medicinal mushrooms: Do they have potential for modern medicine? – An update, Phytomedicine, 66, 2020. Crossref

  2. Zhang Yuchi, Liu Ruoyao, Liu Chunming, Li Sainan, Hou Wanchao, Development of ultrasound‐assisted centrifugal extraction combined with two countercurrent chromatography systems for the simultaneous extraction and isolation of phytochemicals, Journal of Separation Science, 44, 11, 2021. Crossref

  3. Wang Chao, Wang Lirong, Wang Jilong, Li Yu-Peng, Zhang Jun-Sheng, Shan Peipei, Zhang Hua, 21,24-Cyclolanostanes revisited: Structural revision and biological evaluation, Fitoterapia, 156, 2022. Crossref

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