Publication de 12 numéros par an
ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344
Indexed in
Anti-MRSA Activity of Fruiting Body Extracts of Spectacular Rustgill Mushroom, Gymnopilus junonius (Agaricomycetes)
RÉSUMÉ
Despite the great advances in chemotherapeutics, infectious diseases are still one of the leading causes of death worldwide. Among some of the clinically relevant pathogens, methicillin-resistant Staphylococcus aureus (MRSA) ranks as one of the most difficult bacteria to treat. It is a common cause of skin, soft-tissue, and endovascular infections, as well as pneumonia, septic arthritis, endocarditis, osteomyelitis, and sepsis. The research on Basidiomycota is extensive; many species show a broad spectrum of pharmacological activities, including antimicrobial activity. The vast majority of the literature to date generally focuses on screening the antibacterial properties of mushroom extracts. A gap still exists in the identification of the individual compounds responsible for these properties, and few low molecular weight compounds have been described. Gymnopilus junonius, the big laughter mushroom, grows wild in Uruguay, especially on Eucalyptus spp. plantations; it is known as the "eucalyptus fungus." In this work, we report the bioguided isolation, structural elucidation, and antistaphylococcal activity of the main antimicrobial components of fresh basidiocarps of G. junonius.
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Cheong Peter Chiew Hing, Tan Chon Seng, Fung Shin Yee, Medicinal Mushrooms: Cultivation and Pharmaceutical Impact, in Biology of Macrofungi, 2018. Crossref
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Keekan K. K., Ranadive K. R., Naik P., Sendker J., Padmaraj S. R., Anti-Methicillin-Resistant S. aureus Activity of Fruiting Body and Mycelial Culture Extracts of Xylaria longipes Nitschke (Ascomycota), Pharmaceutical Chemistry Journal, 56, 7, 2022. Crossref