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International Journal of Medicinal Mushrooms
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ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344

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International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v6.i3.50
10 pages

Chemical Analysis as a Quality Control Method for Medicinal Mushroom and Fungi Extracts

Xian-guo He
Mushroom Science Laboratory, 1025 Conger St. #6, Eugene, OR 97402 USA
John Seleen
Mushroom Science Laboratory, JHS Natural Products, P.O. Box 50398, Eugene, OR 97405, USA


There has been a much greater awareness of the value of medicinal mushroom extracts as dietary supplements in the last few years in the US. There is also more concern about the quality and potency of these mushroom extracts. As with standardized herbal medicine, chemical analytical methods play an important role to ensure accurate labeling by validating identity, purity, strength, and composition of mushroom extracts. The analytical methods used to evaluate polysaccharide content and other bioactive and nutritional compounds in mushroom extracts were developed in our laboratory using high-performance liquid chromatography (HPLC) and proton-nuclear magnetic resonance (proton NMR) techniques. The analytical methods for three of the most commonly used medicinal mushrooms—Coriolus (=Trametes) versicolor (yun zhi, turkey tail); Ganoderma lucidum (ling zhi, reishi); and Cordyceps sinensis (cordyceps, caterpillar fungus)—are discussed as examples in this article.