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International Journal of Medicinal Mushrooms

Publication de 12  numéros par an

ISSN Imprimer: 1521-9437

ISSN En ligne: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Medically Significant White-Rot Basidiomycetes: Metabolic and Biochemical Characteristics

Volume 7, Numéro 3, 2005, pp. 386-387
DOI: 10.1615/IntJMedMushrooms.v7.i3.360
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RÉSUMÉ

Cultural investigations of white-rot fungi began in the middle of the 20th century due to identification of their capabilities to grow on different nutrient substrates and to exist for long periods in the mycelium stage. This peculiarity of white-rot fungi makes possible their conservation ex situ in culture collections. The ability of basidiome formation during cultivation permits use of some edible white-rot Basidiomycetes for fruit body production, identification, and verification of strains during experimental conditions. The high enzymatic potential of white-rot fungi and their ability to grow in and on substrates permits their use in various types of wastes.
Physiological investigations of white-rot fungi established different peculiarities of the second metabolism of this fungi group. It was shown that many low-molecular weight compounds isolated from white-rot Basidiomycetes determine their flavor, pigmentation, and biological activities. The properties, structures, and characteristics of activities of many terpenoid, alkaloid, phenylquinoid, and anthraquinoid metabolites were established. At present some mushrooms produce substances used in aromatherapy and in the preparation of sanative beverages (i.e., Marasmius sp., Gloeophyllum odoratum (Wulfen) Imazeki, Lentinus edodes). Others are used in the preparation of medicinal drugs containing mucidin, inotodiol, and ganodermanes (i.e., Oudemansiella mucida (Schrad.) Hohn., Inonotus obliquus (Ach. ex Pers.) Pilat, Ganoderma lucidum). High-molecular weight substances such as polysaccharides are also the products of the second metabolism of white-rot basidiomycetes. Today, polysaccharides are the main constituents of some drugs and dietary supplements well known in countries of the southeast regions on Earth. These medicinal products are obtained by fermentation—white-rot Basidiomycetes such as Lentinus edodes, Trametes sp., Schizophyllum commune Fr.:Fr., and some others.
Investigations of the hydrolytic enzymes of white-rot fungi allow indicating the presence of different types of proteases and obtaining the secreted fibrinolytic proteases from Flammulina and Coprinus species and milk clothing enzymes from Mycena pura (Pers.:Fr.) P. Kumm., Irpex lacteus (Fr.) Fr., and Sparassis crispa (Wulfen) Fr. In the last three decades, the enzymatic activity of white-rot Basidiomycetes has been causing great interest, resulting in active investigations. It was shown that among Gem-, Flavin-, and Cu-containing oxidases produced by these fungi, the main role in degrading lignin belonged to lignin peroxidases, manganese peroxidases, and laccases. Biochemical investigations of some species from families Polyporaceae, Ganodermataceae, and Strophariaceae have shown that these white-rot Basidiomycetes produce different oxidases, among which laccases were the main enzymes. Some characteristics of isolated laccases were investigated in cooperation with colleagues from the Bach Biochemistry Institute RAS. Great interest in the practical use of oxidative enzymes of Basidiomycetes is explained in their chemical and catalytic features. The possibility of oxidation of different aromatic, principally phenolic substances to quinones is now very well known in different areas of industry and medicine.

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