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International Journal of Medicinal Mushrooms

Publication de 12  numéros par an

ISSN Imprimer: 1521-9437

ISSN En ligne: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Genoprotective Activity of Edible and Medicinal Mushroom Components

Volume 6, Numéro 1, 2004, 14 pages
DOI: 10.1615/IntJMedMushr.v6.i1.10
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RÉSUMÉ

Hot (100 °C) and cold (20 °C) water extracts of the fruit bodies of selected mushroom species have been tested for their ability to prevent H2O2-induced oxidative damage to cellular DNA using the single-cell gel electrophoresis ("Comet") assay. Highest genoprotection was observed with cold water and hot water extracts of Agaricus bisporus (J.Lge) Imbach and Ganoderma lucidum (W. Curt.:Fr.) Lloyd fruit bodies, respectively. The genoprotective effect of A. bisporus is associated with a heat-labile protein that has been purified following salt fractionation, combined with ion-exchange, hydrophobic interaction, and adsorption chromatography. Based on catalytic and electrophoretic properties and enzyme inhibition studies, the protein was identified as tyrosinase. The genoprotective effect of the protein is dependent upon the enzyme-catalyzed conversion of tyrosine to L-DOPA and subsequent conversion of this metabolite to tyrosinase-generated L-DOPA oxidation products such as dopaquinone. We propose that these oxidation products trigger cellular processes that upregulate the overall antioxidant status of the cell and could be incorporated into preventive strategies and treatments of pathological conditions associated with elevated oxidative DNA damage and other manifestations of increased oxidative stress.

CITÉ PAR
  1. Collopy Patrick D., Royse Daniel J., Characterization of Phytase Activity from Cultivated Edible Mushrooms and Their Production Substrates, Journal of Agricultural and Food Chemistry, 52, 25, 2004. Crossref

  2. Yousefi Neptun, Jones Mitchell, Bismarck Alexander, Mautner Andreas, Fungal chitin-glucan nanopapers with heavy metal adsorption properties for ultrafiltration of organic solvents and water, Carbohydrate Polymers, 253, 2021. Crossref

  3. Mautner Andreas, Wintner Ernst, Fungal Chitin-Glucan: Renewable Nanofibrils for Water Treatment and Structural Materials, in Polymer-Based Advanced Functional Materials for Energy and Environmental Applications, 2022. Crossref

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