Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
Critical Reviews™ in Eukaryotic Gene Expression
Facteur d'impact: 2.156 Facteur d'impact sur 5 ans: 2.255 SJR: 0.649 SNIP: 0.599 CiteScore™: 3

ISSN Imprimer: 1045-4403
ISSN En ligne: 2162-6502

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukarGeneExpr.v20.i2.60
pages 157-170

Protein Flexibility as a Biosignal

Qinyi Zhao
China rehabilitation research center


Dynamic properties of a protein are crucial for all protein functions, and those of signaling proteins are closely related to the biological function of living beings. The protein flexibility signal concept can be used to analyze this relationship. Protein flexibility controls the rate of protein conformational change and influences protein function. The modification of protein flexibility results in a change of protein activity. The logical nature of protein flexibility cannot be explained by applying the principles of protein three-dimensional structure theory or conformation concept. Signaling proteins show high protein flexibility. Many properties of signaling can be traced back to the dynamic natures of signaling protein. The action mechanism of volatile anesthetics and universal cellular reactions are related to flexibility in the change of signaling proteins. We conclude that protein dynamics is an enzyme-enhanced process, called dynamicase.

Articles with similar content:

Driving Mechanisms of Passive and Active Transport Across Cellular Membranes as the Mechanisms of Cell Metabolism and Development as well as the Mechanisms of Cellular Distance Reactions on Hormonal Expression and the Immune Response
Critical Reviews™ in Eukaryotic Gene Expression, Vol.21, 2011, issue 3
Michail R. Ponizovskiy
Target Genes and Cellular Regulators of the Мус Transcription Complex
Critical Reviews™ in Eukaryotic Gene Expression, Vol.8, 1998, issue 3-4
Elizabeth J. Taparowsky, Mette A. Peters
Current Major Advances in the Regulation of Milk Protein Gene Expression
Critical Reviews™ in Eukaryotic Gene Expression, Vol.24, 2014, issue 4
Xi Qian , Feng-Qi Zhao
Homogeneously-sheared compressible turbulence at the rapid distortion limit: Interaction between velocity and thermodynamic fluctuations
S. Suman, Rebecca L. Bertsch, Sharath S. Girimaji
Biophysical and Biochemical Models of Mechanisms of Cellular Development via the Cellular Cycle in Normal Tissue, Cancerous Tissue, and Inflammatory Processes
Critical Reviews™ in Eukaryotic Gene Expression, Vol.23, 2013, issue 2
Michail R. Ponizovskiy