Publication de 6 numéros par an
ISSN Imprimer: 1045-4403
ISSN En ligne: 2162-6502
Indexed in
Nuclear Hormone Receptors and Adipogenesis
RÉSUMÉ
Adipocytes provide a model cell system for exploring the complexities of nuclear hormone receptor transcriptional regulation. Adipocytes produce lipid and cholesterol metabolites which can serve as activating ligands for many of the classic and "orphan" nuclear hormone receptors. At the same time, nuclear hormone receptors directly control adipocyte commitment. The recently described nuclear hormone receptor coactivators and corepressors provide an additional level of complexity to this system. This review emphasizes available in vitro and in vivo models and discusses them in the context of current controversies and future experimental directions.
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Lacey D.C., Simmons P.J., Graves S.E., Hamilton J.A., Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation, Osteoarthritis and Cartilage, 17, 6, 2009. Crossref
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Le Thien P., Sun Miao, Luo Xin, Kraus W. Lee, Greene Geoffrey L., Dahlman-Wright Karin, Mapping ERβ Genomic Binding Sites Reveals Unique Genomic Features and Identifies EBF1 as an ERβ Interactor, PLoS ONE, 8, 8, 2013. Crossref
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Pilbeam Carol C., Harrison John R., Raisz Lawrence G., Prostaglandins and Bone Metabolism, in Principles of Bone Biology, 2002. Crossref
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Couse John F., Korach Kenneth S., Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?, Endocrine Reviews, 20, 3, 1999. Crossref
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Munsakul Natee, Bahn Rebecca S., Adipogenesis and TSH Receptor Expression, in Thyroid Eye Disease, 14, 2001. Crossref
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Rim Jong‐Seop, Mynatt Randall L., Gawronska‐Kozak Barbara, Mesenchymal stem cells from the outer ear: a novel adult stem cell model system for the study of adipogenesis, The FASEB Journal, 19, 9, 2005. Crossref
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Kim Ghi Su, Hong Jeong Soo, Kim Seung Wook, Koh Jung-Min, An Chung Sun, Choi Je-Yong, Cheng Su-Li, Leptin Induces Apoptosis via ERK/cPLA2/Cytochrome c Pathway in Human Bone Marrow Stromal Cells, Journal of Biological Chemistry, 278, 24, 2003. Crossref
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Goodson Michael L., Mengeling Brenda J., Jonas Brian A., Privalsky Martin L., Alternative mRNA Splicing of Corepressors Generates Variants That Play Opposing Roles in Adipocyte Differentiation, Journal of Biological Chemistry, 286, 52, 2011. Crossref