Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
Critical Reviews™ in Biomedical Engineering
SJR: 0.207 SNIP: 0.376 CiteScore™: 0.79

ISSN Imprimer: 0278-940X
ISSN En ligne: 1943-619X

Volumes:
Volume 47, 2019 Volume 46, 2018 Volume 45, 2017 Volume 44, 2016 Volume 43, 2015 Volume 42, 2014 Volume 41, 2013 Volume 40, 2012 Volume 39, 2011 Volume 38, 2010 Volume 37, 2009 Volume 36, 2008 Volume 35, 2007 Volume 34, 2006 Volume 33, 2005 Volume 32, 2004 Volume 31, 2003 Volume 30, 2002 Volume 29, 2001 Volume 28, 2000 Volume 27, 1999 Volume 26, 1998 Volume 25, 1997 Volume 24, 1996 Volume 23, 1995

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.2016016540
pages 33-45

Neural Correlates of Cognitive Modulation of Pain Perception in the Human Brainstem and Cervical Spinal Cord using Functional Magnetic Resonance Imaging: A Review

Roxanne H. Leung
Center for Neuroscience Studies, Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario K7L 3N6, Canada
Patrick W. Stroman
Centre for Neuroscience Studies, Queen's University, 2nd floor, Botterell Hall, 18 Stuart Street, Kingston, ON, Canada K7L 3N6; Department of Physics, Queen's University, Kingston, ON, Canada, K7L 3N6

RÉSUMÉ

Pain is a multifaceted and malleable sensory experience that is processed at all levels of the central nervous system (CNS). The experience of pain can vary widely across a healthy population and even within an individual and can be influenced by cognitive factors such as attention, expectation, suggestion, and attitudes. The neurophysiological role of attention in cognitive modulation of pain is the focus for the work presented in this review. Behavioral studies show that pain perception was reduced under cognitive loads that placed a continuous demand on executive functions such as working memory. Neuroimaging, pharmacological studies, and electrophysiological studies provide evidence that the underpinnings of cognitive modulation of pain involve a network of descending modulation of pain among cortical and brainstem structures. However, the role and relationship of subcortical regions in the brainstem and spinal cord during cognitive modulation of pain are not well understood. This review examines the neurophysiology of pain, processing in the CNS, and how cognitive factors such as attention can modulate nociceptive signaling and alter the perception of pain, especially at the subcortical level.


Articles with similar content:

Chronic Pain: We Should Not Underestimate the Contribution of Neural Plasticity
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.26, 2014, issue 1-2
David A. Rice, Gwyn N. Lewis
Executive Function: Application in the Rehabilitation of Chronic Pain
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.24, 2012, issue 3-4
Zakir Uddin, Victoria Galea, Joy C. MacDermid
Locomotion in Patients with Spinal Cord Injury
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.12, 2000, issue 2
V. Dietz
Optimizing Outcome in the Injured Worker with Low Back Pain
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.11, 1999, issue 2
Scott F. Nadler, Todd P. Stitik, Gerard A. Malanga
Functional Magnetic Resonance Imaging of the Human Brainstem and Cervical Spinal Cord during Cognitive Modulation of Pain
Critical Reviews™ in Biomedical Engineering, Vol.44, 2016, issue 1-2
Patrick W. Stroman, Roxanne H. Leung