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Critical Reviews™ in Biomedical Engineering
SJR: 0.207 SNIP: 0.376 CiteScore™: 0.79

ISSN Imprimer: 0278-940X
ISSN En ligne: 1943-619X

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Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.v29.i3.120
pages 493-501

Laser Radiation Control in Photodynamic Therapy of Tumors

N. F. Kovtonyuk
"'Kometa' Central Research Institute" Federal State Unitary Enterprise, Academy for Technological Sciences of Russian Federation, Russia
A. V. Ivanov
Laser Tumor Diagnostics and Therapy Laboratory Head at the Scientific Research Institute of Experimental Tumor Diagnostics and Therapy, N. N. Blokhin Russian Oncologic Scientific Center, Russia
A. G. Polutov
Scientific and Technical Promotional Center, "'Kometa' Central Research Institute" Federal State Unitary Enterprise, Russia

RÉSUMÉ

This article presents the ideology and basic principles of designing diagnostic and therapeutic medical systems for treating malignant tumors by means of photosensitizers. The designed system is based on optoelectronic devices, which realize selective laser tumor destruction during photodynamic therapy. A distinguishing feature of this system is that laser-beam formation is performed in real time. This enables one to follow changes in the tumor shape during the treatment. As a result of this study, a photodynamic technique for selective phototreatment was developed and tested. Moreover, We determined light doses for such treatment.


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