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Critical Reviews™ in Biomedical Engineering
SJR: 0.26 SNIP: 0.375 CiteScore™: 1.4

ISSN Imprimer: 0278-940X
ISSN En ligne: 1943-619X

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Volume 48, 2020 Volume 47, 2019 Volume 46, 2018 Volume 45, 2017 Volume 44, 2016 Volume 43, 2015 Volume 42, 2014 Volume 41, 2013 Volume 40, 2012 Volume 39, 2011 Volume 38, 2010 Volume 37, 2009 Volume 36, 2008 Volume 35, 2007 Volume 34, 2006 Volume 33, 2005 Volume 32, 2004 Volume 31, 2003 Volume 30, 2002 Volume 29, 2001 Volume 28, 2000 Volume 27, 1999 Volume 26, 1998 Volume 25, 1997 Volume 24, 1996 Volume 23, 1995

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.2016019123
pages 153-166

Ebers, DaVinci, and Euler: Calculating the Pulse. Assumptions, Challenges, and Opportunities in Mathematical Modeling of Aortic Flow

Hisham M. F. Sherif
Cardiac Surgery, Christiana Hospital, 4755 Ogletown-Stanton Road, Newark, DE 19718; Department of Biomedical Engineering, University of Delaware, Newark, DE 19711

RÉSUMÉ

Mathematical modeling of flow in the circulatory system, particularly the arterial system, has long relied on old equations derived from the study of fluid mechanics in rigid tubes, which does not account for the cyclic distension of the vessel or the effects of intraluminal forces on wall components. An understanding of the current scientific evidence and the limitations of such assumptions is essential for adequate computational modeling of the circulatory system. Improved interdisciplinary communication among the basic science, medical, surgical, and biomedical engineering communities should prove to be beneficial in developing safer, more effective, and more reliable tools and devices that are more consistent with physiological processes within the body.


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