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Critical Reviews™ in Biomedical Engineering
SJR: 0.207 SNIP: 0.376 CiteScore™: 0.79

ISSN Imprimer: 0278-940X
ISSN En ligne: 1943-619X

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Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.v30.i123.30
pages 37-54

Signal Processing and Physiological Modeling-Part II: Depth Model-Driven Analysis

Jean-Louis Coatrieux
Universite de Rennes I Campus Beaulieu F-35042 Rennes Cedex France


In this second of two articles on signal processing, we explore the coupling between modeling and signal processing and the critical importance of well-posed clinical questions or hypotheses, as well as a deep knowledge of the underlying mechanisms of such coupling. Our approach consists of building models either as open-loop simulators allowing us to analyze the influence of one or several internal variables on the observations, or as dynamic systems that can enhance our understanding of these underlying mechanisms to be identified in order to lead to an explanative interpretation. These explorations are illustrated by epileptic network and cardiac models, both derived at the macroscopic level.

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