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Critical Reviews™ in Immunology

Publication de 6  numéros par an

ISSN Imprimer: 1040-8401

ISSN En ligne: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

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CD5 Signal Transduction: Positive or Negative Modulation of Antigen Receptor Signaling

Volume 20, Numéro 4, 2000, 12 pages
DOI: 10.1615/CritRevImmunol.v20.i4.30
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RÉSUMÉ

The CD5 lymphocyte surface glycoprotein is a coreceptor involved in the modulation of antigen-specific receptor-mediated activation and differentiation signals. Although first considered a costimulatory molecule in mature peripheral T cells, recent studies of CD5−/− mice have opened the possibility that CD5 may also mediate inhibitory signals that attenuate TCR/CD3- and BCR-mediated triggering in thymocytes and a subgroup of B cells (B-1a cells), respectively. The ultimate molecular basis for these differential modulatory properties of CD5, depending on the context of lymphocyte subset and differentiation stage, are presently unknown and are an issue of current intensive investigation. Here, we review recent reports, both contradictory and complementary, focused on CD5-mediated molecular intracellular signaling events that could provide the basis for its immunomodulatory properties.

CITÉ PAR
  1. König Rolf, Zhou Wenhong, T Lymphocytes, in Handbook of Cell Signaling, 2003. Crossref

  2. Vilà Josep M., Gimferrer Idoia, Padilla Olga, Arman Mònica, Places Lourdes, Simarro María, Vives Jordi, Lozano Francisco, Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases, European Journal of Immunology, 31, 4, 2001. Crossref

  3. König Rolf, Signal Transduction in T Lymphocytes, in Handbook of Cell Signaling, 2010. Crossref

  4. Sigal Leonard H., Basic Science for the Clinician 54, Journal of Clinical Rheumatology, 18, 2, 2012. Crossref

  5. Garza-Garcia Acely, Esposito Diego, Rieping Wolfgang, Harris Richard, Briggs Cherry, Brown Marion H., Driscoll Paul C., Three-dimensional Solution Structure and Conformational Plasticity of the N-terminal Scavenger Receptor Cysteine-rich Domain of Human CD5, Journal of Molecular Biology, 378, 1, 2008. Crossref

  6. Sarrias M.R., Padilla O., Monreal Y., Carrascal M., Abian J., Vives J., Yelamos J., Lozano F., Biochemical characterization of recombinant and circulating human Spalpha, Tissue Antigens, 63, 4, 2004. Crossref

  7. Wada Taizo, Kurokawa Toshiro, Toma Tomoko, Shibata Fumie, Tone Yumi, Hashida Yoko, Kaya Hiroyasu, Yoshida Takashi, Yachie Akihiro, Immunophenotypic analysis of Epstein?Barr virus (EBV)-infected CD8+T cells in a patient with EBV-associated hemophagocytic lymphohistiocytosis, European Journal of Haematology, 79, 1, 2007. Crossref

  8. Roa Nelly S., Ordoñez-Rueda Diana, Chávez-Rios Jesús R., Raman Chander, García-Zepeda Eduardo A., Lozano Francisco, Soldevila Gloria, The carboxy-terminal region of CD5 is required for c-CBL mediated TCR signaling downmodulation in thymocytes, Biochemical and Biophysical Research Communications, 432, 1, 2013. Crossref

  9. Morris John C., Waldmann Thomas A., Janik John E., Receptor-Directed Therapy of T-Cell Leukemias and Lymphomas, Journal of Immunotoxicology, 5, 2, 2008. Crossref

  10. Wada Taizo, Yasumi Takahiro, Toma Tomoko, Hori Masayuki, Maeda Sayaka, Umeda Katsutsugu, Heike Toshio, Adachi Souichi, Usami Ikuya, Yachie Akihiro, Munc13-4 deficiency with CD5 downregulation on activated CD8+T cells, Pediatrics International, 56, 4, 2014. Crossref

  11. Ordoñez-Rueda Diana, Lozano Francisco, Sarukhan Adelaida, Raman Chander, Garcia-Zepeda Eduardo A., Soldevila Gloria, Increased numbers of thymic and peripheral CD4+ CD25+ Foxp3+ cells in the absence of CD5 signaling, European Journal of Immunology, 39, 8, 2009. Crossref

  12. Howard Kristina E., Burkhard Mary Jo, FIV Infection Induces Unique Changes in Phenotype and Cellularity in the Medial Iliac Lymph Node and Intestinal IEL, AIDS Research and Human Retroviruses, 23, 5, 2007. Crossref

  13. Theise Neil D, New principles of cell plasticity, Comptes Rendus Biologies, 325, 10, 2002. Crossref

  14. Rahman Abu Nasar Md. Aminoor, Snibson Kenneth J., Lee Chee Seong, Meeusen Els N.T., Effects of implantation and early pregnancy on the expression of cytokines and vascular surface molecules in the sheep endometrium, Journal of Reproductive Immunology, 64, 1-2, 2004. Crossref

  15. Howard Kristina E., Fisher Ingrid L., Dean Gregg A., Jo Burkhard Mary, Methodology for isolation and phenotypic characterization of feline small intestinal leukocytes, Journal of Immunological Methods, 302, 1-2, 2005. Crossref

  16. Hawiger Daniel, Masilamani Revati F, Bettelli Estelle, Kuchroo Vijay K, Nussenzweig Michel C, Immunological Unresponsiveness Characterized by Increased Expression of CD5 on Peripheral T Cells Induced by Dendritic Cells In Vivo, Immunity, 20, 6, 2004. Crossref

  17. Perez-Chacon Gema, Vargas Juan A., Jorda Julia, Morado Marta, Rosado Silvia, Martin-Donaire Trinidad, Losada-Fernandez Ignacio, Rebolleda Nerea, Perez-Aciego Paloma, CD5 provides viability signals to B cells from a subset of B-CLL patients by a mechanism that involves PKC, Leukemia Research, 31, 2, 2007. Crossref

  18. Fenutría Rafael, Martinez Vanesa G., Simões Inês, Postigo Jorge, Gil Victor, Martínez-Florensa Mario, Sintes Jordi, Naves Rodrigo, Cashman Kevin S., Alberola-Ila José, Ramos-Casals Manel, Soldevila Gloria, Raman Chander, Merino Jesús, Merino Ramón, Engel Pablo, Lozano Francisco, Driscoll Paul C., Transgenic Expression of Soluble Human CD5 Enhances Experimentally-Induced Autoimmune and Anti-Tumoral Immune Responses, PLoS ONE, 9, 1, 2014. Crossref

  19. Cenit Maria Carmen, Martínez-Florensa Mario, Consuegra Marta, Bonet Lizette, Carnero-Montoro Elena, Armiger Noelia, Caballero-Baños Miguel, Arias Maria Teresa, Benitez Daniel, Ortego-Centeno Norberto, de Ramón Enrique, Sabio José Mario, García–Hernández Francisco J., Tolosa Carles, Suárez Ana, González-Gay Miguel A., Bosch Elena, Martín Javier, Lozano Francisco, Rieux-Laucat Frederic, Analysis of Ancestral and Functionally Relevant CD5 Variants in Systemic Lupus Erythematosus Patients, PLoS ONE, 9, 11, 2014. Crossref

  20. Huang Yi-Chun, Hung Shao-Wen, Jan Tong-Rong, Liao Kuang-Wen, Cheng Chiung-Hsiang, Wang Yu-Shan, Chu Rea-Min, CD5-low expression lymphocytes in canine peripheral blood show characteristics of natural killer cells, Journal of Leukocyte Biology, 84, 6, 2008. Crossref

  21. Vasquez Marcos, Simões Inês, Consuegra-Fernández Marta, Aranda Fernando, Lozano Francisco, Berraondo Pedro, Exploiting scavenger receptors in cancer immunotherapy: Lessons from CD5 and SR-B1, European Journal of Immunology, 47, 7, 2017. Crossref

  22. Freitas Claudia, Johnson Deborah, Weber K., T Cell Calcium Signaling Regulation by the Co-Receptor CD5, International Journal of Molecular Sciences, 19, 5, 2018. Crossref

  23. Cho Jae-Ho, Sprent Jonathan, TCR tuning of T cell subsets, Immunological Reviews, 283, 1, 2018. Crossref

  24. Boulton Ian C., Gray-Owen Scott D., Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytes, Nature Immunology, 3, 3, 2002. Crossref

  25. von Stackelberg Arend, Monoclonal Antibodies in Paediatric Acute Lymphoblastic Leukemia, in New Agents for the Treatment of Acute Lymphoblastic Leukemia, 2011. Crossref

  26. Benetti F., Briso A. L. F., Carminatti M., Araújo Lopes J. M., Barbosa J. G., Ervolino E., Gomes‐Filho J. E., Cintra L. T. A., The presence of osteocalcin, osteopontin and reactive oxygen species‐positive cells in pulp tissue after dental bleaching, International Endodontic Journal, 52, 5, 2019. Crossref

  27. Franzke Anke, Piao Wenji, Lauber Jörg, Gatzlaff Patricia, Könecke Christian, Hansen Wiebke, Schmitt-Thomsen Angela, Hertenstein Bernd, Buer Jan, Ganser Arnold, G-CSF as immune regulator in T cells expressing the G-CSF receptor: implications for transplantation and autoimmune diseases, Blood, 102, 2, 2003. Crossref

  28. Martínez Vanesa Gabriela, Moestrup Søren Kragh, Holmskov Uffe, Mollenhauer Jan, Lozano Francisco, Sibley David R., The Conserved Scavenger Receptor Cysteine-Rich Superfamily in Therapy and Diagnosis, Pharmacological Reviews, 63, 4, 2011. Crossref

  29. Voisinne Guillaume, García‐Blesa Antonio, Chaoui Karima, Fiore Frédéric, Bergot Elise, Girard Laura, Malissen Marie, Burlet‐Schiltz Odile, Gonzalez de Peredo Anne, Malissen Bernard, Roncagalli Romain, Co‐recruitment analysis of theCBLandCBLBsignalosomes in primary T cells identifiesCD5 as a key regulator ofTCR‐induced ubiquitylation, Molecular Systems Biology, 12, 7, 2016. Crossref

  30. Velasco-de Andrés María, Casadó-Llombart Sergi, Català Cristina, Leyton-Pereira Alejandra, Lozano Francisco, Aranda Fernando, Soluble CD5 and CD6: Lymphocytic Class I Scavenger Receptors as Immunotherapeutic Agents, Cells, 9, 12, 2020. Crossref

  31. Rane Sanket, Das Rituparna, Ranganathan Vidya, Prabhu Savit, Das Arundhoti, Mattoo Hamid, Durdik Jeannine Marie, George Anna, Rath Satyajit, Bal Vineeta, Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function, BMC Biology, 12, 1, 2014. Crossref

  32. Bamberger Martina, Santos Ana Mafalda, Gonçalves Carine M., Oliveira Marta I., James John R., Moreira Alexandra, Lozano Franscisco, Davis Simon J., Carmo Alexandre M., A New Pathway of CD5 Glycoprotein-mediated T Cell Inhibition Dependent on Inhibitory Phosphorylation of Fyn Kinase, Journal of Biological Chemistry, 286, 35, 2011. Crossref

  33. Herzig Carolyn TA, Waters Ray W, Baldwin Cynthia L, Telfer Janice C, Evolution of the CD163 family and its relationship to the bovine gamma delta T cell co-receptor WC1, BMC Evolutionary Biology, 10, 1, 2010. Crossref

  34. Blevins Lance K., Zhou Jiajun, Crawford Robert B., Kaminski Norbert E., Identification of a Sensitive Human Immunological Target of Aryl Hydrocarbon Receptor Activation: CD5+ Innate-Like B Cells, Frontiers in Immunology, 12, 2021. Crossref

  35. Vera Jorge, Fenutría Rafael, Cañadas Olga, Figueras Maite, Mota Rubén, Sarrias Maria-Rosa, Williams David L., Casals Cristina, Yelamos José, Lozano Francisco, The CD5 ectodomain interacts with conserved fungal cell wall components and protects from zymosan-induced septic shock-like syndrome, Proceedings of the National Academy of Sciences, 106, 5, 2009. Crossref

  36. Theise N.D., Harris R., Postmodern Biology: (Adult) (Stem) Cells Are Plastic, Stochastic, Complex, and Uncertain, in Stem Cells, 174, 2006. Crossref

  37. Gimferrer Idoia, Farnós Montse, Calvo Maria, Mittelbrunn Marı́a, Enrich Carlos, Sánchez-Madrid Francisco, Vives Jordi, Lozano Francisco, The Accessory Molecules CD5 and CD6 Associate on the Membrane of Lymphoid T Cells, Journal of Biological Chemistry, 278, 10, 2003. Crossref

  38. Wada Taizo, Sakakibara Yasuhisa, Nishimura Ryosei, Toma Tomoko, Ueno Yasuhisa, Horita Seiki, Tanaka Taihei, Nishi Masanori, Kato Keisuke, Yasumi Takahiro, Ohara Osamu, Yachie Akihiro, Down-regulation of CD5 expression on activated CD8+ T cells in familial hemophagocytic lymphohistiocytosis with perforin gene mutations, Human Immunology, 74, 12, 2013. Crossref

  39. Fink Dorte Rosenbek, Holm Dorte, Schlosser Anders, Nielsen Ole, Latta Markus, Lozano Francisco, Holmskov Uffe, Elevated numbers of SCART1+ γδ T cells in skin inflammation and inflammatory bowel disease, Molecular Immunology, 47, 9, 2010. Crossref

  40. Zhu Zilu, Li Ran, Li Hao, Zhou Tong, Davis Randall S., FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling, Proceedings of the National Academy of Sciences, 110, 14, 2013. Crossref

  41. Sarrias Maria-Rosa, Farnós Montserrat, Mota Rubén, Sánchez-Barbero Fernando, Ibáñez Anna, Gimferrer Idoia, Vera Jorge, Fenutría Rafael, Casals Cristina, Yélamos José, Lozano Francisco, CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock, Proceedings of the National Academy of Sciences, 104, 28, 2007. Crossref

  42. Soldevila Gloria, Raman Chander, Lozano Francisco, The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease, Current Opinion in Immunology, 23, 3, 2011. Crossref

  43. Axtell Robert C., Webb Matthew S., Barnum Scott R., Raman Chander, Cutting Edge: Critical Role for CD5 in Experimental Autoimmune Encephalomyelitis: Inhibition of Engagement Reverses Disease in Mice, The Journal of Immunology, 173, 5, 2004. Crossref

  44. Vilà Josep M., Calvo Javier, Places Lourdes, Padilla Olga, Arman Mònica, Gimferrer Idoia, Aussel Claude, Vives Jordi, Lozano Francisco, Role of Two Conserved Cytoplasmic Threonine Residues (T410 and T412) in CD5 Signaling, The Journal of Immunology, 166, 1, 2001. Crossref

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