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Journal of Long-Term Effects of Medical Implants

Publication de 4  numéros par an

ISSN Imprimer: 1050-6934

ISSN En ligne: 1940-4379

SJR: 0.184 SNIP: 0.485 CiteScore™:: 1.1 H-Index: 39

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Viscosupplementation for Knee Osteoarthritis: Current Evidence and Recommendations

Volume 23, Numéro 2-03, 2013, pp. 151-159
DOI: 10.1615/JLongTermEffMedImplants.2013009871
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RÉSUMÉ

Osteoarthritis (OA) is the most common joint disorder worldwide and is a leading cause of pain and disability. Appropriate management of younger patients with milder disease remains a challenging area of intense research. Viscosupplementation attempts to restore the biomechanical and biochemical functions of normal synovial fluid hyaluronic acid. Several preparations with varying characteristics are currently available. The literature suggests a small benefit and relative safety, but several recent large meta-analyses have reported conflicting results. Major clinical guidelines provide inconclusive recommendations. Viscosupplementation may be a viable option in younger patients with milder OA where other non-operative modalities are also only modestly successful, but further investigation is clearly warranted. Limitations due to study heterogeneity, outcome reporting, and bias can each be addressed with improved research methodology.

CITÉ PAR
  1. McElheny Kathryn, Toresdahl Brett, Ling Daphne, Mages Keith, Asif Irfan, Comparative Effectiveness of Alternative Dosing Regimens of Hyaluronic Acid Injections for Knee Osteoarthritis: A Systematic Review, Sports Health: A Multidisciplinary Approach, 11, 5, 2019. Crossref

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