Publication de 4 numéros par an
ISSN Imprimer: 0731-8898
ISSN En ligne: 2162-6537
Indexed in
Positron Emission Tomography Imaging of Tumor Response after Photodynamic Therapy
RÉSUMÉ
Positron emission tomography (PET) imaging is a powerful noninvasive tool allowing physiological and biochemical processes to be investigated in vivo at the molecular level. In the clinics, it is currently being used to detect and stage cancer and to assess tumor response following therapy. In cancer research, at the preclinical level, PET in conjunction with a dedicated high-resolution small animal scanner can play an important role in drug development as well as in the evaluation of novel treatment protocols. In this paper, we review the use of PET in assessing tumor response to photodynamic therapy (PDT) and discuss its potential role in the development of novel photosensitizers. This molecular imaging modality is particularly promising for the real-time evaluation of tumor response to therapy both in terms of treatment efficacy and action mechanism.
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Huang Zheng, Haider Masoom A., Kraft Susan, Chen Qun, Blanc Dominique, Wilson Brian C., Hetzel Fred W., Magnetic resonance imaging correlated with the histopathological effect of Pd-bacteriopheophorbide (Tookad) photodynamic therapy on the normal canine prostate gland, Lasers in Surgery and Medicine, 38, 7, 2006. Crossref
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Master Alyssa, Livingston Megan, Sen Gupta Anirban, Photodynamic nanomedicine in the treatment of solid tumors: Perspectives and challenges, Journal of Controlled Release, 168, 1, 2013. Crossref
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Fleshker Shimrit, Preise Dina, Kalchenko Vyacheslav, Scherz Avigdor, Salomon Yoram, Prompt Assessment of WST11-VTP Outcome Using Luciferase Transfected Tumors Enables Second Treatment and Increase in Overall Therapeutic Rate, Photochemistry and Photobiology, 84, 5, 2008. Crossref
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Wilson B.C., Photodynamic Techniques in Medicine, in Comprehensive Biomedical Physics, 2014. Crossref
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Wilson Brian C, Patterson Michael S, The physics, biophysics and technology of photodynamic therapy, Physics in Medicine and Biology, 53, 9, 2008. Crossref
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Byrne A T, O'Connor A E, Hall M, Murtagh J, O'Neill K, Curran K M, Mongrain K, Rousseau J A, Lecomte R, McGee S, Callanan J J, O'Shea D F, Gallagher W M, Vascular-targeted photodynamic therapy with BF2-chelated Tetraaryl-Azadipyrromethene agents: a multi-modality molecular imaging approach to therapeutic assessment, British Journal of Cancer, 101, 9, 2009. Crossref
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Johansson Ann, Andersson-Engels Stefan, Photodynamic Therapy - the Quest for Improved Dosimetry in the Management of Solid Tumors, in Laser Imaging and Manipulation in Cell Biology, 2010. Crossref
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Huang Zheng, Xu Heping, Meyers Arlen D., Musani Ali I., Wang Luowei, Tagg Randall, Barqawi Al B., Chen Yang K., Photodynamic Therapy for Treatment of Solid Tumors — Potential and Technical Challenges, Technology in Cancer Research & Treatment, 7, 4, 2008. Crossref