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Journal of Environmental Pathology, Toxicology and Oncology

Publication de 4  numéros par an

ISSN Imprimer: 0731-8898

ISSN En ligne: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Micronucleus Test in Fish from a Pampasic Pond (Argentina): An Estimation of the Presence of Genotoxic Compounds

Volume 20, Numéro 4, 2001, 7 pages
DOI: 10.1615/JEnvironPatholToxicolOncol.v20.i4.90
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RÉSUMÉ

The Los Padres pond is one of the commonly shallow, polymictic lakes from the so-called depressed Pampa (Argentina). Its watershed includes one affluent, named Los Padres creek, which flows through horticultural lands wherein great amounts of pesticides are applied. Opposite to this stream, the pond drains into La Tapera creek that is the effluent running toward the sea. Many studies have confirmed the capacity of various pesticides to induce genetic damage. The use of micronucleus (MN) tests in fish has enabled us to detect the presence of contaminants in the lake water and to evaluate their genotoxic effects. For this purpose, water samples were collected during April, August, and December 1999 from both creeks characterized by different environmental conditions. In the laboratory, specimens of tetras Cheirodon interruptus (Pisces, Characidae) were reared in water samples from the two creeks. Control fish were kept in drinking water. Fifteen individuals from each experimental group were sacrificed after 24-, 48-, and 72-hour exposure intervals. Micronucleus frequency in fish erythrocytes was determined, and the Kruskal–Wallis test for statistic analysis was used. We made the following observations: (1) Highly significant differences occurred in MN frequency between the control group and the samples from both creeks. (2) An increase in MN frequency was evident in specimens sampled from the affluent input during the month of December. These results allowed us to conclude that the increase in MN frequency observed in fish belonging to both sampling sites would indicate the existence of genotoxic compounds in the Los Padres pond. The high MN frequency in fish collected near Los Padres creek inlet might be related to the polluted load transported by the affluent and discharged into the lake’s surface waters. Future work would allow us to develop efficient methods for predicting the presence of genotoxic contaminants. It would be possible then to propose strategies for regulating and decreasing the sources of pollution that affect human health.

CITÉ PAR
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  2. Ohe Takeshi, Watanabe Tetsushi, Wakabayashi Keiji, Mutagens in surface waters: a review, Mutation Research/Reviews in Mutation Research, 567, 2-3, 2004. Crossref

  3. Vera Candioti Josefina, Soloneski Sonia, Larramendy Marcelo L., Genotoxic and cytotoxic effects of the formulated insecticide Aficida® on Cnesterodon decemmaculatus (Jenyns, 1842) (Pisces: Poeciliidae), Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 703, 2, 2010. Crossref

  4. Petcoff Gladys M., Díaz Alcira O., Escalante Alicia H., Goldemberg Adriana L., Histology of the liver of Oligosarcus jenynsii (Ostariophysi, Characidae) from Los Padres Lake, Argentina, Iheringia. Série Zoologia, 96, 2, 2006. Crossref

  5. D’Agostini Francesco, La Maestra Sebastiano, Micronuclei in Fish Erythrocytes as Genotoxic Biomarkers of Water Pollution: An Overview, in Reviews of Environmental Contamination and Toxicology Volume 258, 258, 2021. Crossref

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