Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
Journal of Environmental Pathology, Toxicology and Oncology
Facteur d'impact: 1.625 Facteur d'impact sur 5 ans: 1.63 SJR: 0.402 SNIP: 0.613 CiteScore™: 2.3

ISSN Imprimer: 0731-8898
ISSN En ligne: 2162-6537

Journal of Environmental Pathology, Toxicology and Oncology

DOI: 10.1615/JEnvironPatholToxicolOncol.2017020213
pages 217-228

Molecular Mechanisms of UVA-Induced Melanoma

Xiao Pudroma
Department of Physics, Tibet University, Lhasa, China
Gongsang Duoji
Department of Mathematics, Tibet University, Lhasa, China
Mantas Grigalavicius
Department of Radiation Biology, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Montebello, 0310 Oslo, Norway
Duan Jie
Department of Physics, Tibet University, Lhasa, China
Asta Juzeniene
Department of Radiation Biology, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Montebello, 0310 Oslo, Norway

RÉSUMÉ

Cutaneous melanoma is a deadly skin cancer, resulting from malignant transformation of melanocytes. Long-wave ultraviolet radiation (315−400 nm) is able to damage DNA, cause mutations, and induce melanoma. However, the exact mechanisms of UVA-induced cutaneous melanoma remain a matter of debate. In this review, we give a brief characterization of the most important elements in the photobiology of UVA in melanomagenesis.


Articles with similar content:

Targeting the Regulatory Machinery of BIM for Cancer Therapy
Critical Reviews™ in Eukaryotic Gene Expression, Vol.22, 2012, issue 2
Steven Grant, Hisashi Harada
Arsenic-Mediated Cellular Signal Transduction, Transcription Factor Activation, and Aberrant Gene Expression: Implications in Carcinogenesis
Journal of Environmental Pathology, Toxicology and Oncology, Vol.21, 2002, issue 4
Krystyna Frenkel, Chengfeng Yang
Immunology Comes Full Circle in Melanoma While Specific Immunity Is Unleashed to Eliminate Metastatic Disease, Inflammatory Products of Innate Immunity Promote Resistance
Critical Reviews™ in Oncogenesis, Vol.21, 2016, issue 1-2
Elizabeth A. Grimm
Raf Kinase Inhibitory Protein (RKIP) as a Metastasis Suppressor: Regulation of Signaling Networks in Cancer
Critical Reviews™ in Oncogenesis, Vol.19, 2014, issue 6
Marsha Rich Rosner, Ali E. Yesilkanal
Dual Role of p21 in the Progression of Cancer and Its Treatment
Critical Reviews™ in Eukaryotic Gene Expression, Vol.26, 2016, issue 1
Amna Parveen, Whang Wan Kyunn, Muhammad Sajid Hamid Akash, Kanwal Rehman