DOI: 10.1615/ICHMT.2008.CHT
ISBN Print: 978-1-56700-253-9
ISSN: 2578-5486
CLUSTER FLUID DYNAMICS MODEL OF BIOCRYSTAL GROWTH
SINOPSIS
A mathematical model has been developed and numerical studies have been performed of the process of crystallization of lysozyme from an aqueous solution of its corresponding protein influenced by the spatial distribution of the precipitating agent's (NaCl) concentration and the controlling pin-point action of the temperature. The mathematical model describes crystal nucleation and growth depending on the local supersaturation value and heat-mass transfer within the entire volume of the solution including the protein crystals. Heat and mass transfer is described by means of fhe Navier-Stokes equations in the Boussinesq approximation with regard to both thermogravitational and concentration-based convection types.