RT Journal Article ID 64a5151f638a56ee A1 Halin, Cornelia A1 Neri, Dario T1 Antibody-Based Targeting of Angiogenesis JF Critical Reviews™ in Therapeutic Drug Carrier Systems JO CRT YR 2001 FD 2001-06-01 VO 18 IS 3 OP 41 AB Angiogenesis—the sprouting of new blood vessels from pre-existing ones—is a characteristic feature of relevant diseases such as cancer, some blinding ocular disorders, rheumatoid arthritis, and psoriasis. This article reviews recent progress in the generation of monoclonal antibodies, which recognize and target new blood vessels in vivo, while sparing mature vessels and healthy tissues. The use of such antibodies as selective "molecular vehicles" is likely to open new important diagnostic and therapeutic opportunities. PB Begell House LK https://www.dl.begellhouse.com/journals/3667c4ae6e8fd136,5434574b034d7796,64a5151f638a56ee.html