%0 Journal Article
%A Chien, Rao-Chi
%A Lin, Lan-Min
%A Chang, Yuan-Hua
%A Lin, Yu-Chieh
%A Wu, Pei-Hsuan
%A Asatiani, Mikheil D.
%A Wasser, Sophie-Gabrielle
%A Krakhmalnyi, Maxim
%A Agbarya, Abed
%A Wasser, Solomon P.
%A Mau, Jeng-Leun
%D 2016
%I Begell House
%K flavonoids, fruiting body, inflammation, medicinal mushrooms, mycelium, phenols
%N 11
%P 999-1009
%R 10.1615/IntJMedMushrooms.v18.i11.50
%T Anti-Inflammation Properties of Fruiting Bodies and Submerged Cultured Mycelia of Culinary-Medicinal Higher Basidiomycetes Mushrooms
%U https://www.dl.begellhouse.com/journals/708ae68d64b17c52,07a0495239bddf76,4ba191eb4578ed4d.html
%V 18
%X This research shows the phenolic composition and anti-inflammation properties of fruiting bodies and mycelia of 15 strains of 12 species of higher Basidiomycetes medicinal mushrooms. In this research, 15 extracts were prepared and their effects on inflammation-related mediators in RAW 264.7 cells were evaluated. In the extracts, amounts of total phenols ranged from 8.47 to 70.32 gallic acid equivalents mg/g and amounts of flavonoids ranged from 0.13 to 15.21 rutin equivalents mg/g. The production of nitric oxide, tumor necrosis factor-α, and interleukin-6 was decreased at different levels by these extracts, whereas the production of interleukin-10 was increased by 6 of the extracts. Overall, Cordyceps militaris fruiting bodies, Grifola frondosa fruiting bodies, and Ophiocordyceps sinensis mycelia might be used to ameliorate inflammatory responses.
%8 2016-12-20