RT Journal Article ID 300cb1390f0ffd97 A1 Wasser, Solomon P. A1 Kovalenko, Oleksiy G. A1 Polishchuk, Olena N. T1 Virus Resistance Induced by Glucuronoxylomannan Isolated from Submerged Cultivated Yeast-like Cell Biomass of Medicinal Yellow Brain Mushroom Tremella mesenterica Ritz.: Fr. (Heterobasidiomycetes) in Hypersensitive Host Plants JF International Journal of Medicinal Mushrooms JO IJM YR 2009 FD 2009-06-11 VO 11 IS 2 SP 199 OP 205 K1 glucuronoxylomannan K1 polysaccharides K1 medicinal mushrooms K1 Tremella mesenterica K1 tobacco mosaic virus K1 virus-induced resistance K1 Nicotiana tabacum K1 Datura stramonium AB The ability of exopolysaccharides produced by medicinal mushroom Tremella mesenterica to influence the mechanisms of plant resistance to viruses has been studied. It was established that neutral polysaccharides (100−1000 μg/mL) can inhibit the formation of local lesions induced by the tobacco mosaic virus (TMV) (86%−96%) in Nicotiana tabacum and Datura stramonium plants. Acid water-soluble glucuronoxylomannan (GXM) in a concentration of 1000−2500 μg/mL activates the mechanisms of virus localization and also the acquired virus resistance (AVR) in plants supersensitive to TMV de novo. This is confirmed by the fact that actinomycin D (10−20 μg/mL), an inhibitor of DNA-dependent RNA-polymerase, partially inhibits the development of AVR. The possibility of using the natural product GXM as an instrument to study the mechanism of AVR as a method to decrease viral infection lesions in plants is under discussion. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,0be754666c89dfcc,300cb1390f0ffd97.html