RT Journal Article ID 1ce9410755efda08 A1 Jiang, Huabei A1 Ramesh, Sathappan A1 Bartlett, Matthew T1 Combined Optical and Fluorescence Imaging for Breast Cancer Detection and Diagnosis JF Critical Reviews™ in Biomedical Engineering JO CRB YR 2000 FD 2000-08-01 VO 28 IS 3&4 SP 371 OP 375 AB In this article, we present a novel approach that combines the best aspects of both endogenous optical imaging and exogenous fluorescent lifetime and yield imaging for breast cancer detection and diagnosis. Using this approach, spatial distributions of optical properties, fluorescence lifetime, and yield in tissue can be reconstructed from measured excitation and emission data at the surface of the breast tissue by regularized inverse algorithms. We show images from simulated data, as well as images from experimental data using tissue-like phantom materials in the laboratory. PB Begell House LK https://www.dl.begellhouse.com/journals/4b27cbfc562e21b8,657c94ee3fd00c46,1ce9410755efda08.html