%0 Journal Article
%A Zhou, Changyan
%A Qiao, Yanru
%A Tang, Qingjiu
%A Jia, Wei
%A Liu, Yanfang
%A Wu, Aizhong
%D 2013
%I Begell House
%K medicinal mushrooms, Maitake mushroom, Grifola frondosa, small-molecule polysaccharide, purification, immune activity, macrophages
%N 2
%P 145-152
%R 10.1615/IntJMedMushr.v15.i2.30
%T Purification and Characterization of a Novel Small-Molecule Polysaccharide from the Maitake Medicinal Mushroom Grifola frondosa (Higher Basidiomycetes)
%U https://www.dl.begellhouse.com/journals/708ae68d64b17c52,72e9ed69099c0eef,0c97877d7783367f.html
%V 15
%X A novel small-molecule polysaccharide with a molecular mass of 2.6 kDa, was isolated from the culinary-medicinal Maitake mushroom Grifola frondosa. GFPS is composed of fucose, rhamnose, galactose, glucose, and mannose; galactose, glucose, and mannose were the dominant monosaccharides. Absorption peaks at 1077 cm−1, 1024 cm−1, and 873 cm−1, as revealed by infrared spectrum, suggesting that GFPS consists of pyranoside. GFPS significantly enhanced the production of nitric oxide and secretion of cytokines (tumor necrosis factor-α, interleukin-1β, and interleukin-δ) from macrophages in vitro. These results indicate that this novel small-molecule polysaccharide might be beneficial for immune defense.
%8 2013-03-22