%0 Journal Article %A Zhou, Changyan %A Qiao, Yanru %A Tang, Qingjiu %A Jia, Wei %A Liu, Yanfang %A Wu, Aizhong %D 2013 %I Begell House %K medicinal mushrooms, Maitake mushroom, Grifola frondosa, small-molecule polysaccharide, purification, immune activity, macrophages %N 2 %P 145-152 %R 10.1615/IntJMedMushr.v15.i2.30 %T Purification and Characterization of a Novel Small-Molecule Polysaccharide from the Maitake Medicinal Mushroom Grifola frondosa (Higher Basidiomycetes) %U https://www.dl.begellhouse.com/journals/708ae68d64b17c52,72e9ed69099c0eef,0c97877d7783367f.html %V 15 %X A novel small-molecule polysaccharide with a molecular mass of 2.6 kDa, was isolated from the culinary-medicinal Maitake mushroom Grifola frondosa. GFPS is composed of fucose, rhamnose, galactose, glucose, and mannose; galactose, glucose, and mannose were the dominant monosaccharides. Absorption peaks at 1077 cm−1, 1024 cm−1, and 873 cm−1, as revealed by infrared spectrum, suggesting that GFPS consists of pyranoside. GFPS significantly enhanced the production of nitric oxide and secretion of cytokines (tumor necrosis factor-α, interleukin-1β, and interleukin-δ) from macrophages in vitro. These results indicate that this novel small-molecule polysaccharide might be beneficial for immune defense. %8 2013-03-22