Publicado 12 números por año
ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
Indexed in
Production of Polysaccharide by Culinary-Medicinal Mushroom Agaricus brasiliensis S. Wasser et al. LPB 03 (Agaricomycetideae) in Submerged Fermentation and Its Antitumor Effect
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SINOPSIS
Studies were performed on the production of extracellular polysaccharide in submerged culture of Agaricus brasiliensis Wasser et al. and the effects of different carbon and nitrogen sources individually and in combinations on production. The polysaccharide produced was evaluated for its antitumor action against Sarcoma 180. Glucose and yeast extract gave the best combination of carbon and nitrogen sources for the polysaccharide production. The biomass yield and polysaccharide produced were 222.3 and 10.867 mg/50 mL (dry wt), respectively, at the concentration of 20 g/L glucose and 2 g/L yeast extract with the medium containing MgSO4Ч7H2O (0.1%) and K2HPO4Ч3H2O (0.1%) at pH 6.0 and 32°C after the 9 days' static cultivation. The extracellular polysaccharide showed strong antitumor activity against Sarcoma 180. Complete regression ratio of 50% and suppression ratio percentage of 72.19% were observed.
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Dalla-Santa Herta S., Rubel Rosália, Vitola Francisco M.D., Buchi Dorli, Di-Bernardi Raffaello P., Moreno Andréa N., Lima-Filho José H.C., Dalla-Santa Osmar R., Gern Juliana C., Monteiro Marta C., Fernandes Luis C., Soccol Carlos R., Agaricus brasiliensismycelium supplementation in Sarcoma 180tumour-bearing mice reverses the immune response induced by the tumour, Food and Agricultural Immunology, 24, 2, 2013. Crossref
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Navegantes Kely C., Albuquerque Rosyana F. V., Dalla-Santa Herta S., Soccol Carlos R., Monteiro Marta C., Agaricus brasiliensismycelium and its polysaccharide modulate the parameters of innate and adaptive immunity, Food and Agricultural Immunology, 24, 4, 2013. Crossref
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Ko Huey-Jiun, Song Airong, Lai Min-Nan, Ng Lean-Teik, Antioxidant and Antiradical Activities of Wu Ling Shen in a Cell Free System, The American Journal of Chinese Medicine, 37, 04, 2009. Crossref
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Mokochinski João Benhur, Sovrani Vanessa, Dalla Santa Herta Stutz, Felsner Maria Lurdes, Sawaya Alexandra Christine Helena Franklan, González-Borrero Pedro Pablo, Bataglion Giovana Anceski, Eberlin Marcos Nogueira, Torres Yohandra Reyes, Biomass and Sterol Production from Vegetal Substrate Fermentation Using A garicus brasiliensis , Journal of Food Quality, 38, 3, 2015. Crossref
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Mokochinski João B., López Begoña G. C., Sovrani Vanessa, Dalla Santa Herta S., González-Borrero Pedro Pablo, Sawaya Alexandra Christine Helena F., Schmidt Eduardo M., Eberlin Marcos N., Torres Yohandra R., Production ofAgaricus brasiliensismycelium from food industry residues as a source of antioxidants and essential fatty acids, International Journal of Food Science & Technology, 50, 9, 2015. Crossref
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BERTÉLI MÍRIA B.D., LOPES ANA D., COLLA ITARUÃ M., LINDE GIANI A., COLAUTO NELSON B., Agaricus subrufescens: substratum nitrogen concentration and mycelial extraction method on antitumor activity, Anais da Academia Brasileira de Ciências, 88, 4, 2016. Crossref
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Junior Letti Luiz A., Destéfanis Vítola Francisco M., Vinícius de Melo Pereira Gilberto, Karp Susan G., Pedroni Medeiros Adriane B., Ferreira da Costa Eduardo S., Bissoqui Lucas, Soccol Carlos R., Solid-State Fermentation for the Production of Mushrooms, in Current Developments in Biotechnology and Bioengineering, 2018. Crossref
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Mao Xian-Bing, Zhong Jian-Jiang, Significant effect of NH4+ on cordycepin production by submerged cultivation of medicinal mushroom Cordyceps militaris, Enzyme and Microbial Technology, 38, 3-4, 2006. Crossref