Publicado 12 números por año
ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344
Indexed in
Effects of Higher Basidiomycetes Mushrooms on the Hippocampal Slices in Rats
SINOPSIS
Effects of water and ethanol extracts on spike activity of 28 neurons from the hippocampal stratum pyramidale (CA1 region) were studied in nine higher Basidiomycetes species: Boletus edulis (Bull.: Fr.), Xerocomus badius Fr., Lentinus edodes (Berk.) Sing., Lactarius turpis (Weinm.) Fr., Amanita muscaria (L.: Fr.) Hook., Stropharia aeruginosa (Curt.: Fr.) Quel., Armillariella mellea (Vahl.: Fr.) P. Karst, Hypholoma fasciculare (Huds.: Fr.) Kumm., and Piptoporus betulinus (Bull.: Fr.) P. Karst. Lactarius turpis and Lentinus edodes extracts caused the neuron excitation; S. aeruginosa, H. fasciculare, and P. betulinus extracts caused excitation or inhibition; A. muscaria, B. edulis, X. badius, and A. mellea clearly expressed inhibition responses. Extracts of A. muscaria rarely caused excitation or inhibition−excitation responses. Whether the nature of the responses was inhibitory or excitatory was not associated with the extract concentration. Neuron responses occurred only with the application of extracts in the majority of the studied species. In some cases the neuron excitation was also manifest after the termination of application of extracts of L. edodes, A. mellea, P. betulinus (for 1−5 min.) and especially A. muscaria when inhibition or excitation lasted for 6 to 12 min.