Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
International Journal of Medicinal Mushrooms
Factor de Impacto: 1.423 Factor de Impacto de 5 años: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v13.i5.50
pages 455-464

Enhanced Production of Medicinal Polysaccharide by Submerged Fermentation of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidium (W.Curt.:Fr.) P. Karst. Using Statistical and Evolutionary Optimization Methods

Gurunathan Baskar
Department of Biotechnology, St. Joseph's College of Engineering, Chennai, India
Shree Rajesh K. Lakshmi Jai Sathya
Department of Biotechnology, St. Joseph's College of Engineering, Chennai − 600 119, India

SINOPSIS

Statistical and evolutionary optimization of media composition was employed for the production of medicinal exopolysaccharide (EPS) by Lingzhi or Reishi medicinal mushroom Ganoderma lucidium MTCC 1039 using soya bean meal flour as low-cost substrate. Soya bean meal flour, ammonium chloride, glucose, and pH were identified as the most important variables for EPS yield using the two-level Plackett-Burman design and further optimized using the central composite design (CCD) and the artificial neural network (ANN)-linked genetic algorithm (GA). The high value of coefficient of determination of ANN (R2 = 0.982) indicates that the ANN model was more accurate than the second-order polynomial model of CCD (R2 = 0.91) for representing the effect of media composition on EPS yield. The predicted optimum media composition using ANN-linked GA was soybean meal flour 2.98%, glucose 3.26%, ammonium chloride 0.25%, and initial pH 7.5 for the maximum predicted EPS yield of 1005.55 mg/L. The experimental EPS yield obtained using the predicted optimum media composition was 1012.36 mg/L, which validates the high degree of accuracy of evolutionary optimization for enhanced production of EPS by submerged fermentation of G. lucidium.


Articles with similar content:

Employment of ARTP to Generate Phellinus baumii (Agaricomycetes) Strain with High Flavonoids Production and Validation by Liquid Fermentation
International Journal of Medicinal Mushrooms, Vol.21, 2019, issue 12
Di Wu, Dehui Qu, Yan Yang, Fuchun Jiang, Henan Zhang, Jing-Song Zhang, Wenhan Wang, Yating Dong
Optimization of the Process for Producing Biomass and Exopolysaccharide from the King Tuber Oyster Mushroom, Pleurotus tuber-regium (Agaricomycetes), for Biotechnological Applications
International Journal of Medicinal Mushrooms, Vol.21, 2019, issue 4
Comfort Olukemi Bamigboye, Joanna Felicity Dames, Agbaje Lateef, Julius Kola Oloke, Mike Burton
Production of Basidiomata and Ligninolytic Enzymes by the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Licuri (Syagrus coronata) Wastes in Brazil
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 12
Luciana Porto de Souza Vandenberghe, Aline Simoes da Rocha Bispo, Helio Mitoshi Kamida, Maria Gabriela Bello Koblitz, Aristoteles Goes-Neto, Thais Almeida de Menezes
Nutritional Requirements for Mycelial Growth of Milk-White Toothed Mushroom, Irpex lacteus (Agaricomycetes), in Submerged Culture
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 9
Xiaoming Dong, Xinhua Song, Caihong Dong
Medium Selection for Exopolysaccharide and Biomass Production in Submerged Cultures of Culinary-Medicinal Mushrooms from Turkey
International Journal of Medicinal Mushrooms, Vol.12, 2010, issue 1
Mustafa Yamac, Meltem Kizilcik