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International Journal of Medicinal Mushrooms

Publicado 12 números por año

ISSN Imprimir: 1521-9437

ISSN En Línea: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Screening of Indian Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes): A UPC2-SQD-MS Approach

Volumen 18, Edición 2, 2016, pp. 177-189
DOI: 10.1615/IntJMedMushrooms.v18.i2.80
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SINOPSIS

Oriental medicinal mushroom Ganoderma lucidum has been widely used for the promotion of health and longevity owing to its various bioactive constituents. Therefore, comprehending metabolomics of different G. lucidum parts could be of paramount importance for investigating their pharmacological properties. Ultra-performance convergence chromatography (UPC2) along with mass spectrometry (MS) is an emerging technique that has not yet been applied for metabolite profiling of G. lucidum. This study has been undertaken to establish metabolomics of the aqueous extracts of mycelium (GLM), fruiting body (GLF), and their mixture (GLMF) using ultra-performance convergence chromatography single quadrupole mass spectrometry (UPC2-SQD-MS). Aqueous extracts of G. lucidum prepared using an accelerated solvent extraction technique have been characterized for their mycochemical activities in terms of total flavonoid content, 1,1-diphenyl-2-picryl-hydrazyl scavenging activity, and ferric ion reducing antioxidant power. The UPC2-SQD-MS technique has been used for the first time for metabolite profiling of G. lucidum on a Princeton Diol column (4.6 × 250 mm; 5 µm) using supercritical CO2 (solvent) and 20 mM ammonium acetate in methanol (co-solvent). In the present study, UPC2-SQD-MS was found to be a rapid, efficient, and high-throughput analytical technique, whose coupling to principal component analysis (PCA) and phytochemical evaluation could be used as a powerful tool for elucidating metabolite diversity between mycelium and fruiting body of G. lucidum. PCA showed a clear distinction in the metabolite compositions of the samples. Mycochemical studies revealed that overall GLF possessed better antioxidant properties among the aqueous extracts of G. lucidum.

CITADO POR
  1. Mishra Jigni, Joshi Anivesh, Rajput Rakhee, Singh Kaushlesh, Bansal Anju, Misra Kshipra, Phenolic Rich Fractions from Mycelium and Fruiting Body of Ganoderma lucidum Inhibit Bacterial Pathogens Mediated by Generation of Reactive Oxygen Species and Protein Leakage and Modulate Hypoxic Stress in HEK 293 Cell Line, Advances in Pharmacological Sciences, 2018, 2018. Crossref

  2. Rakhee , Mishra Jigni, Sharma Raj K., Misra Kshipra, Characterization Techniques for Herbal Products, in Management of High Altitude Pathophysiology, 2018. Crossref

  3. Zhu Liping, Wu Min, Li Peng, Zhou Yanfei, Zhong Jinyi, Zhang Zhiqiang, Li Ye, Yao Weixi, Xu Jianhua, High-Pressure Supercritical CO2 Extracts of Ganoderma lucidum Fruiting Body and Their Anti-hepatoma Effect Associated With the Ras/Raf/MEK/ERK Signaling Pathway, Frontiers in Pharmacology, 11, 2020. Crossref

  4. Molineau Jérémy, Meunier Manon, Noireau Angéline, Fougère Laëtitia, Petit Anne-Marie, West Caroline, Analysis of flavonoids with unified chromatography-electrospray ionization mass spectrometry—method development and application to compounds of pharmaceutical and cosmetic interest, Analytical and Bioanalytical Chemistry, 412, 24, 2020. Crossref

  5. Ahmad Md Faruque, Ganoderma lucidum: Persuasive biologically active constituents and their health endorsement, Biomedicine & Pharmacotherapy, 107, 2018. Crossref

  6. Li Changqin, Cui Yiping, Lu Jie, Meng Lijun, Ma Changyang, Liu Zhenhua, Zhang Yan, Kang Wenyi, Spectrum-effect relationship of immunologic activity of Ganoderma lucidum by UPLC-MS/MS and component knock-out method, Food Science and Human Wellness, 10, 3, 2021. Crossref

  7. Liu Tao, Zhou Jianchuan, Li Wenxiang, Rong Xiaoping, Gao Yan, Zhao Lihong, Fan Yu, Zhang Jianyun, Ji Cheng, Ma Qiugang, Effects of sporoderm-broken spores of Ganoderma lucidum on growth performance, antioxidant function and immune response of broilers, Animal Nutrition, 6, 1, 2020. Crossref

  8. Lesellier Eric, West Caroline, Supercritical fluid chromatography for the analysis of natural dyes: From carotenoids to flavonoids, Journal of Separation Science, 45, 1, 2022. Crossref

  9. Li Yanhong, Liang Wei, Han Yunlin, Zhao Wenjie, Wang Siyuan, Qin Chuan, Triterpenoids and Polysaccharides from Ganoderma lucidum Improve the Histomorphology and Function of Testes in Middle-Aged Male Mice by Alleviating Oxidative Stress and Cellular Apoptosis, Nutrients, 14, 22, 2022. Crossref

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